• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Nucleoside and nucleobase transporters in parasitic protozoa.寄生原生动物中的核苷和核碱基转运蛋白。
Eukaryot Cell. 2004 Apr;3(2):245-54. doi: 10.1128/EC.3.2.245-254.2004.
2
Purine and pyrimidine transport in pathogenic protozoa: from biology to therapy.致病原生动物中的嘌呤和嘧啶转运：从生物学到治疗
FEMS Microbiol Rev. 2005 Nov;29(5):987-1020. doi: 10.1016/j.femsre.2005.03.004. Epub 2005 Jul 1.
3
Pyrimidine transport activities in trypanosomes.锥虫中的嘧啶转运活性。
Trends Parasitol. 2007 May;23(5):187-9; discussion 190. doi: 10.1016/j.pt.2007.03.003. Epub 2007 Mar 19.
4
Nucleoside/nucleobase transport and metabolism by microvascular endothelial cells isolated from ENT1-/- mice.从 ENT1-/- 小鼠中分离的微血管内皮细胞的核苷/碱基转运和代谢。
Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H847-56. doi: 10.1152/ajpheart.00018.2010. Epub 2010 Jun 11.
5
Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes.来自非洲锥虫的首个核碱基转运蛋白基因的分子与功能特性
Mol Biochem Parasitol. 2003 Aug 31;130(2):101-10. doi: 10.1016/s0166-6851(03)00167-1.
6
Adaptive responses to purine starvation in Leishmania donovani.利什曼原虫对嘌呤饥饿的适应性反应。
Mol Microbiol. 2010 Oct;78(1):92-107. doi: 10.1111/j.1365-2958.2010.07327.x.
7
Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii.刚地弓形虫中高亲和力核苷和核碱基转运体的鉴定与表征
Int J Parasitol. 2003 Jul 30;33(8):821-31. doi: 10.1016/s0020-7519(03)00091-2.
8
Equilibrative nucleoside transporters-A review.平衡核苷转运体——综述
Nucleosides Nucleotides Nucleic Acids. 2017 Jan 2;36(1):7-30. doi: 10.1080/15257770.2016.1210805. Epub 2016 Oct 19.
9
Molecular genetic analysis of purine nucleobase transport in Leishmania major.硕大利什曼原虫嘌呤核碱基转运的分子遗传学分析
Mol Microbiol. 2007 Jun;64(5):1228-43. doi: 10.1111/j.1365-2958.2007.05730.x.
10
Nucleoside transporters of parasitic protozoa.寄生原生动物的核苷转运体。
Trends Parasitol. 2001 Mar;17(3):142-5. doi: 10.1016/s1471-4922(00)01806-7.

引用本文的文献

1
Substrate and inhibitor specificity of Plasmodium nucleoside transporters ENT1 orthologs.疟原虫核苷转运体ENT1直系同源物的底物和抑制剂特异性
J Biol Chem. 2025 Feb;301(2):108115. doi: 10.1016/j.jbc.2024.108115. Epub 2024 Dec 24.
2
hexanic extract triggers alteration in the energy metabolism in epimastigotes of .己烷提取物引发了……的前鞭毛体能量代谢的改变。 （原句中“of”后面缺少具体内容）
Front Mol Biosci. 2023 Sep 25;10:1206074. doi: 10.3389/fmolb.2023.1206074. eCollection 2023.
3
Transcriptomic analysis of the adaptation to prolonged starvation of the insect-dwelling epimastigotes.昆虫寄生的前鞭毛体对长期饥饿适应的转录组分析。
Front Cell Infect Microbiol. 2023 Apr 6;13:1138456. doi: 10.3389/fcimb.2023.1138456. eCollection 2023.
4
Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.疟原虫核苷转运蛋白 PfENT1 的底物识别和抑制机制的结构基础。
Nat Commun. 2023 Mar 28;14(1):1727. doi: 10.1038/s41467-023-37411-1.
5
Development of Novel Anti-Leishmanials: The Case for Structure-Based Approaches.新型抗利什曼原虫药物的研发：基于结构方法的实例
Pathogens. 2022 Aug 22;11(8):950. doi: 10.3390/pathogens11080950.
6
Genetic disruption of nucleoside transporter 4 reveals its critical roles in malaria parasite sporozoite functions.遗传干扰核苷转运蛋白 4 揭示其在疟原虫子孢子功能中的关键作用。
Pathog Glob Health. 2023 May;117(3):284-292. doi: 10.1080/20477724.2022.2112880. Epub 2022 Aug 24.
7
An RNA-binding protein complex regulates the purine-dependent expression of a nucleobase transporter in trypanosomes.一种RNA结合蛋白复合物调节锥虫中一种核碱基转运蛋白的嘌呤依赖性表达。
Nucleic Acids Res. 2021 Apr 19;49(7):3814-3825. doi: 10.1093/nar/gkab181.
8
Transient Down-Regulation of Nucleoside Transporter 3 Gene Expression as a Drug Target in Antisense RNA Technology.作为反义RNA技术药物靶点的核苷转运体3基因表达的瞬时下调
Iran J Parasitol. 2019 Jan-Mar;14(1):111-119.
9
Dependence of parasite on host derived ATP: an overview of extracellular nucleotide metabolism in parasite.寄生虫对宿主来源ATP的依赖性：寄生虫细胞外核苷酸代谢概述
J Parasit Dis. 2019 Mar;43(1):1-13. doi: 10.1007/s12639-018-1061-4. Epub 2018 Dec 1.
10
ATPe Dynamics in Protozoan Parasites. Adapt or Perish.原生动物寄生虫中的ATP动力学：适应或灭亡
Genes (Basel). 2018 Dec 27;10(1):16. doi: 10.3390/genes10010016.

本文引用的文献

1
Pyrazolopyrimidine metabolism in parasitic protozoa.吡唑并嘧啶代谢在寄生原生动物中。
Pharm Res. 1984 Sep;1(5):194-203. doi: 10.1023/A:1016365128531.
2
Functional expression and characterization of a purine nucleobase transporter gene from Leishmania major.来自硕大利什曼原虫的嘌呤核碱基转运蛋白基因的功能表达与特性分析
Mol Membr Biol. 2004 Jan-Feb;21(1):11-8. doi: 10.1080/0968768031000140845.
3
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.布氏锥虫中砷剂和双脒的摄取及抗性机制
Eukaryot Cell. 2003 Oct;2(5):1003-8. doi: 10.1128/EC.2.5.1003-1008.2003.
4
Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes.来自非洲锥虫的首个核碱基转运蛋白基因的分子与功能特性
Mol Biochem Parasitol. 2003 Aug 31;130(2):101-10. doi: 10.1016/s0166-6851(03)00167-1.
5
Equilibrative nucleoside transporter family members from Leishmania donovani are electrogenic proton symporters.来自杜氏利什曼原虫的平衡核苷转运体家族成员是生电质子同向转运体。
J Biol Chem. 2003 Sep 12;278(37):35127-34. doi: 10.1074/jbc.M306188200. Epub 2003 Jun 30.
6
Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.来自杜氏利什曼原虫的肌苷-鸟苷转运蛋白的功能分析。保守残基天冬氨酸389和精氨酸393的作用。
J Biol Chem. 2003 Aug 29;278(35):33327-33. doi: 10.1074/jbc.M305141200. Epub 2003 Jun 13.
7
Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.原生动物首个高亲和力核碱基转运蛋白的克隆、异源表达及原位表征
J Biol Chem. 2003 Jun 27;278(26):23502-7. doi: 10.1074/jbc.M301252200. Epub 2003 Apr 21.
8
A Leishmania major nucleobase transporter responsible for allopurinol uptake is a functional homolog of the Trypanosoma brucei H2 transporter.一种负责摄取别嘌呤醇的硕大利什曼原虫核碱基转运蛋白是布氏锥虫H2转运蛋白的功能同源物。
Mol Pharmacol. 2003 Apr;63(4):814-20. doi: 10.1124/mol.63.4.814.
9
Molecular evolution of the equilibrative nucleoside transporter family: identification of novel family members in prokaryotes and eukaryotes.平衡核苷转运蛋白家族的分子进化：原核生物和真核生物中新家族成员的鉴定
Mol Biol Evol. 2002 Dec;19(12):2199-210. doi: 10.1093/oxfordjournals.molbev.a004044.
10
Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions.来自布氏锥虫的六种相关核苷/核碱基转运蛋白具有不同的生化功能。
J Biol Chem. 2002 Jun 14;277(24):21499-504. doi: 10.1074/jbc.M202319200. Epub 2002 Apr 5.

Nucleoside and nucleobase transporters in parasitic protozoa.

作者信息

Landfear Scott M, Ullman Buddy, Carter Nicola S, Sanchez Marco A

机构信息

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97239-3098, USA.

出版信息

Eukaryot Cell. 2004 Apr;3(2):245-54. doi: 10.1128/EC.3.2.245-254.2004.

DOI:10.1128/EC.3.2.245-254.2004
PMID:15075255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC387651/
Abstract
摘要