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一种感知氮的丝裂原活化蛋白激酶调节烟曲霉的分生孢子萌发和生长。

A mitogen-activated protein kinase that senses nitrogen regulates conidial germination and growth in Aspergillus fumigatus.

作者信息

Xue Tao, Nguyen C Kim, Romans Angela, May Gregory S

机构信息

Division of Pathology and Laboratory Medicine and Genes and Development Graduate Program, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

出版信息

Eukaryot Cell. 2004 Apr;3(2):557-60. doi: 10.1128/EC.3.2.557-560.2004.

DOI:10.1128/EC.3.2.557-560.2004
PMID:15075285
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC387654/
Abstract

We show that the mitogen-activated protein (MAP) kinase pathway that responds to osmotic stress in Aspergillus fumigatus is also involved in nutritional sensing. This MAP kinase regulates conidial germination in response to the nitrogen source and is activated upon starvation for either carbon or nitrogen during vegetative growth.

摘要

我们发现，烟曲霉中对渗透胁迫作出反应的丝裂原活化蛋白（MAP）激酶途径也参与营养感知。这种MAP激酶响应氮源调节分生孢子萌发，并在营养生长期间碳或氮饥饿时被激活。

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本文引用的文献

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Mol Plant Microbe Interact. 2003 Sep;16(9):760-8. doi: 10.1094/MPMI.2003.16.9.760.
2
Evidence that the appressorial development in barley powdery mildew is controlled by MAP kinase activity in conjunction with the cAMP pathway.有证据表明，大麦白粉病中附着胞的发育是由丝裂原活化蛋白激酶（MAP激酶）活性与环磷酸腺苷（cAMP）途径共同控制的。
Fungal Genet Biol. 2003 Jun;39(1):94-102. doi: 10.1016/s1087-1845(02)00587-x.
3
An unusual MAP kinase is required for efficient penetration of the plant surface by Ustilago maydis.玉米黑粉菌有效穿透植物表面需要一种特殊的丝裂原活化蛋白激酶。
EMBO J. 2003 May 1;22(9):2199-210. doi: 10.1093/emboj/cdg198.
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Mating, conidiation and pathogenicity of Fusarium graminearum, the main causal agent of the head-blight disease of wheat, are regulated by the MAP kinase gpmk1.禾谷镰刀菌是小麦赤霉病的主要致病菌，其交配、产孢和致病性受促分裂原活化蛋白激酶gpmk1调控。
Curr Genet. 2003 May;43(2):87-95. doi: 10.1007/s00294-003-0379-2. Epub 2003 Mar 7.
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The Hog1 mitogen-activated protein kinase is essential in the oxidative stress response and chlamydospore formation in Candida albicans.Hog1丝裂原活化蛋白激酶在白色念珠菌的氧化应激反应和厚垣孢子形成过程中至关重要。
Eukaryot Cell. 2003 Apr;2(2):351-61. doi: 10.1128/EC.2.2.351-361.2003.
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Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe.寒冷在裂殖酵母粟酒裂殖酵母中诱导应激激活蛋白激酶介导的反应。
Eur J Biochem. 2002 Oct;269(20):5056-65. doi: 10.1046/j.1432-1033.2002.03214.x.
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SakA MAP kinase is involved in stress signal transduction, sexual development and spore viability in Aspergillus nidulans.SakA丝裂原活化蛋白激酶参与构巢曲霉的应激信号转导、有性发育和孢子活力。
Mol Microbiol. 2002 Aug;45(4):1153-63. doi: 10.1046/j.1365-2958.2002.03087.x.
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Ras links cellular morphogenesis to virulence by regulation of the MAP kinase and cAMP signalling pathways in the pathogenic fungus Candida albicans.在致病性真菌白色念珠菌中，Ras通过调节丝裂原活化蛋白激酶（MAP激酶）和环磷酸腺苷（cAMP）信号通路，将细胞形态发生与毒力联系起来。
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A MAP kinase of the vascular wilt fungus Fusarium oxysporum is essential for root penetration and pathogenesis.尖孢镰刀菌这种维管束萎蔫真菌的一种促分裂原活化蛋白激酶对于根部侵染和致病作用至关重要。
Mol Microbiol. 2001 Mar;39(5):1140-52.