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针对年轻患者的起搏器和植入式除颤器治疗的最新进展。

Recent advances in pacemaker and implantable defibrillator therapy for young patients.

作者信息

Walsh Edward P, Cecchin Frank

机构信息

Department of Cardiology, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

出版信息

Curr Opin Cardiol. 2004 Mar;19(2):91-6. doi: 10.1097/00001573-200403000-00004.

Abstract

PURPOSE OF REVIEW

This review is intended to highlight major clinical advances over the past year related to (1). biventricular pacing as a treatment for dilated myopathy, (2). growing clinical experience with implantable cardioverter defibrillators in pediatrics, (3). technical advances in standard antibradycardia pacing, and (4). an appraisal of the newly updated ACC/AHA/NASPE guidelines for device implant in children and adolescents.

RECENT FINDINGS

Complex rhythm devices are being used more frequently in children. Biventricular pacing to improve ventricular contractility is a rapidly evolving technology that has now been applied to children and young adults with intraventricular conduction delay, such as bundle branch block after cardiac surgery. Implantable defibrillators are also being used for an expanding list of conditions, although lead dysfunction is seen as a fairly common complication in active young patients. Guidelines for device implantation have been developed, but the weight of evidence remains somewhat limited by the paucity of pediatric data in this field.

SUMMARY

Thanks to refinements in lead design and generator technology, coupled with rapidly expanding clinical indications, pacemakers and implantable defibrillators have become increasingly important components of cardiac therapy for young patients. Expanded multicenter clinical studies will be needed to develop more objective guidelines for use of this advanced technology.

摘要

综述目的

本综述旨在突出过去一年在以下方面取得的主要临床进展:(1)双心室起搏治疗扩张型心肌病;(2)儿科植入式心脏复律除颤器的临床经验不断积累;(3)标准抗心动过缓起搏技术的进展;(4)对最新更新的美国心脏病学会(ACC)/美国心脏协会(AHA)/北美心脏起搏和电生理学会(NASPE)儿童及青少年器械植入指南的评估。

最新发现

复杂节律器械在儿童中的使用越来越频繁。通过双心室起搏改善心室收缩功能是一项快速发展的技术,现已应用于患有室内传导延迟的儿童和年轻人,如心脏手术后的束支传导阻滞。植入式除颤器也被用于越来越多的病症,尽管在活跃的年轻患者中,导线功能障碍被视为相当常见的并发症。已经制定了器械植入指南,但由于该领域儿科数据匮乏,证据的充分性仍受到一定限制。

总结

得益于导线设计和发生器技术的改进,以及临床适应证的迅速扩大,起搏器和植入式除颤器已成为年轻患者心脏治疗中越来越重要的组成部分。需要开展更多的多中心临床研究,以制定关于使用这种先进技术的更客观的指南。

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