Gastaldello Rene, Hall William W, Gallego Sandra
Laboratory of Human Lymphotropic Virus, Institute of Virology, School of Medicine, National University of Córdoba, Argentina.
J Acquir Immune Defic Syndr. 2004 Mar 1;35(3):301-8. doi: 10.1097/00126334-200403010-00012.
In this report, the results of seroepidemiologic studies of human T-lymphotropic virus type I (HTLV-I) and type II (HTLV-II) infections in different population groups in Argentina have been compiled. The studies have shown a high prevalence of HTLV-I/II infection in blood donors in the provinces in the north of Argentina (1.0% in Jujuy, 0.7% in Salta, and 0.6% in Formosa) and a low prevalence in the provinces in the central region of the country (<or=0.1%). High rates of HTLV-I (0.45%-2.78%) and HTLV-II (2.78%-21.9%) infections have been documented in Native Indian groups and have highlighted the importance of sexual and mother-to-child transmission of the viruses. The presence of HTLV-I/II antibodies in HIV-infected individuals indicates that both viruses are circulating in certain high-risk population groups. HTLV-I/II was detected in intravenous drug users (2.56%-21.7%), homosexual men (0.5-1.33%), prostitutes (0.8%), and hemophiliacs (2.8%). In conclusion, HTLV-I/II infection is circulating in low- and high-risk populations in Argentina, and these findings would support the view that selective screening for HTLV-I/II should be implemented to reduce the spread of infection.
在本报告中，汇总了阿根廷不同人群中I型人类嗜T淋巴细胞病毒（HTLV-I）和II型人类嗜T淋巴细胞病毒（HTLV-II）感染的血清流行病学研究结果。研究表明，阿根廷北部省份的献血者中HTLV-I/II感染率较高（胡胡伊省为1.0%，萨尔塔省为0.7%，福尔摩沙省为0.6%），而该国中部地区省份的感染率较低（≤0.1%）。在印第安原住民群体中记录到较高的HTLV-I感染率（0.45%-2.78%）和HTLV-II感染率（2.78%-21.9%），这突出了病毒的性传播和母婴传播的重要性。HIV感染者中存在HTLV-I/II抗体表明这两种病毒在某些高危人群中传播。在静脉吸毒者（2.56%-21.7%）、男同性恋者（0.5%-1.33%）、妓女（0.8%）和血友病患者（2.8%）中检测到HTLV-I/II。总之，HTLV-I/II感染在阿根廷的低危和高危人群中传播，这些发现支持应实施HTLV-I/II选择性筛查以减少感染传播这一观点。
