Senju R
Second Department of Internal Medicine, Nagasaki University School of Medicine, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Jun;30(6):1056-62.
To elucidate the relationship between clinical and histopathological findings in diffuse panbronchiolitis (DPB), we reviewed 14 open lung biopsy cases clinically suspected of having DPB. According to the histopathological criteria for "PB unit lesion" proposed by Kitaichi in 1988, 11 cases were diagnosed as having DPB; 3 cases were excluded by the criteria. The pathological diagnosis was not concordant with the evaluation according to the clinical diagnostic criteria for DPB previously proposed by Homma et al. in 1983. The present results indicate 1) the necessity to reexamine the pathological criteria for DPB, especially in open lung biopsy cases, and 2) the difficult differential diagnosis between DPB cases and non-DPB ones by current clinical diagnostic criteria.
为阐明弥漫性泛细支气管炎（DPB）临床与组织病理学表现之间的关系，我们回顾了14例临床疑似DPB的开胸肺活检病例。根据北市一于1988年提出的“PB单位病变”组织病理学标准，11例被诊断为DPB；3例被该标准排除。病理诊断与本间等人于1983年先前提出的DPB临床诊断标准评估结果不一致。目前结果表明：1）有必要重新审视DPB的病理标准，尤其是在开胸肺活检病例中；2）按照当前临床诊断标准，DPB病例与非DPB病例之间的鉴别诊断存在困难。
