[阿格拉宾及盐酸11,13-二氢-13-二甲氨基阿格拉宾的抗炎作用]
[Anti-inflammatory effect of arglabin and 11,13-dihydro-13-dimethylaminoarglabin hydrochloride].
作者信息
Abil'daeva A Zh, Pak R N, Kulyiasov A T, Adekenov S M
机构信息
Laboratory of Phytopreparation Technology and Pharmacology, Institute of Phytochemistry, ul. Gazalieva 4, Karaganda, 470032 Kazakhstan.
出版信息
Eksp Klin Farmakol. 2004 Jan-Feb;67(1):37-9.
PMID:15079907
Abstract
The sesquiterpene lactone arglabin, as well as its derivative 11,13-Dihydro-13-dimethylaminoarglabin hydrochloride, exhibit antiexudative and antiproliferative properties on the models of acute aseptic inflammation caused by formalin, carrageenan, and histamine, and on the model of proliferative inflammation accompanying cotton-pellet granuloma.
摘要
倍半萜内酯阿格拉宾及其衍生物11,13-二氢-13-二甲氨基阿格拉宾盐酸盐，在福尔马林、角叉菜胶和组胺引起的急性无菌性炎症模型以及棉球肉芽肿伴随的增殖性炎症模型中均表现出抗渗出和抗增殖特性。
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