Blood Borne Infections Research Center, Academic Center for Education, Culture & Research (ACECR), Razavi Khorasan Branch, Mashhad 91775-1376, Iran.
Department of Experimental Pathology, Microbiology and Immunology, Faculty of Medicine, American University of Beirut, Beirut 1107 2020, Lebanon.
Viruses. 2022 Mar 23;14(4):664. doi: 10.3390/v14040664.
The epidemiology and prevalence of the Human T-cell leukemia virus type-1 (HTLV-1) infection represent a recommended priority by global health agencies. An in-depth revision to update the status of this infection in countries including those of the Eastern Mediterranean Regional Office (EMRO) of the World Health Organization is hence required.
Ninety-seven studies evaluating the HTLV-1 infection in low- and high-risk populations in EMRO countries were retrieved from the international electronic databases and were used to assess the epidemiological status of the infection in these countries.
Most epidemiologic reports were published from Iran, with more than 50% of Iranian prisoners and around 4% of healthy individuals reported to have the infection. In Egypt, a considerable prevalence of the virus spans around 1.11% of blood donors. Foci of HTLV-1 infection are also present in some countries and require a careful epidemiological evaluation. In the other EMRO countries, a lower prevalence that does not exceed 1% was reported.
The epidemiology and prevalence of HTLV-1 in the EMRO countries require a tight revision and update. Published studies reveal a scarce distribution of the virus in the African countries of EMRO, while a lower prevalence is denoted in the Asian countries of EMRO, except in Iran, where the prevalence is high.
人类 T 细胞白血病病毒 1 型（HTLV-1）感染的流行病学和流行率是全球卫生机构推荐的优先事项。因此，需要对包括世界卫生组织东地中海区域办事处（EMRO）国家在内的国家的这种感染状况进行深入修订，以提供最新信息。
从国际电子数据库中检索了 97 项评估 EMRO 国家低危和高危人群中 HTLV-1 感染的研究，用于评估这些国家的感染流行状况。
大多数流行病学报告来自伊朗，超过 50%的伊朗囚犯和约 4%的健康个体报告感染了该病毒。在埃及，相当一部分献血者的病毒携带率约为 1.11%。HTLV-1 感染的病灶也存在于一些国家，需要进行仔细的流行病学评估。在其他 EMRO 国家，报告的流行率低于 1%。
EMRO 国家 HTLV-1 的流行病学和流行率需要进行严格的修订和更新。已发表的研究表明，该病毒在 EMRO 的非洲国家分布稀少，而在 EMRO 的亚洲国家则呈低流行率，伊朗除外，伊朗的流行率很高。
