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The 2001 serological survey in the Czech Republic--parapertussis.

作者信息

Maixnerová M

机构信息

National Reference Laboratory for Pertussis and Parapertussis, Charles University in Prague, 3rd Medical Faculty, Prague, Czech Republic.

出版信息

Cent Eur J Public Health. 2003 Dec;11 Suppl:S23-4.

PMID:15080255
Abstract

The results of the 2001 serological survey of antibodies against parapertussis confirmed a relatively high immunity rate of the Czech population. Prevalence of positive titers of antibodies can reach 60% in children 10 years old and ranges from 40 to 60% in the adult population. A rapid increase of immunity rate of the population suggests a high circulation of B. parapertussis in the population.

摘要

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2
Bordetella parapertussis survives the innate interaction with human neutrophils by impairing bactericidal trafficking inside the cell through a lipid raft-dependent mechanism mediated by the lipopolysaccharide O antigen.副百日咳博德特氏菌通过脂多糖 O 抗原介导的脂筏依赖性机制损害细胞内杀菌性运输，从而在与人类中性粒细胞的先天相互作用中存活下来。
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The O antigen enables Bordetella parapertussis to avoid Bordetella pertussis-induced immunity.O抗原使副百日咳博德特氏菌能够逃避百日咳博德特氏菌诱导的免疫反应。
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