Suppr超能文献

德里的人类狂犬病

Human rabies in Delhi.

作者信息

Chhabra Mala, Ichhpujani R L, Tewari K N, Lal Shiv

机构信息

Zoonosis Division, National Institute of Communicable Diseases, Sham Nath Marg, Delhi, India.

出版信息

Indian J Pediatr. 2004 Mar;71(3):217-20. doi: 10.1007/BF02724273.

Abstract

OBJECTIVE

Analysis of human rabies cases admitted in Infectious Diseases Hospital, Delhi during the course of one year was undertaken to understand the epidemiology of rabies.

METHODS

The data was collected using standardized proforma and was analyzed on EPI Info 6.02 software version. A total of 49.8% of the human rabies came from Delhi and rest belonged to adjoining states of UP (30.3%), Haryana (18.3%), Bihar (0.8%), Punjab (0.4%) and MP (0.4%). Children in the age group 5-14 years fell victim to the disease in significantly higher numbers (36.7%) as compared to other age groups. Male Female ratio was 4:1. Biting animals involved were dog (96.7%), jackal (1.7%), cat (0.8%), monkey (0.4%) and mongoose (0.4%). Majority (78.8%) had Category III exposure. Hydrophobia, which is the pathogonomic feature of human rabies, was present in 95% of cases. Remaining (5%) gave history of animal bite and presented with features of aerophobia, photophobia along with fever, weakness in limbs, parasthesia, and/or paralysis. Significantly higher number (93.4%) did not receive any local wound treatment. Most (91.7%) cases never received any vaccination and remaining were inadequately vaccinated; only five had received 10-14 injections of Neural Tissue Vaccine (NTV) and one child who had multiple bites on face, received 5 doses of NTV, local wound treatment and intramuscular ARS on 3rd day.

RESULT

The data strongly reveals that people who died due to rabies either did not receive any treatment or were inappropriately and inadequately treated. Hence, there is need to educate the community and the health care professionals about the importance of immediate and adequate post exposure treatment. The data also indicates that the epidemiology of the disease has not changed much over the decades.

CONCLUSION

The disease can be prevented with the available tools and all we need to do is to implement them effectively.

摘要

目的

对德里传染病医院一年内收治的人类狂犬病病例进行分析,以了解狂犬病的流行病学情况。

方法

使用标准化表格收集数据,并在EPI Info 6.02软件版本上进行分析。共有49.8%的人类狂犬病病例来自德里,其余病例来自毗邻的北方邦(30.3%)、哈里亚纳邦(18.3%)、比哈尔邦(0.8%)、旁遮普邦(0.4%)和中央邦(0.4%)。5至14岁年龄组的儿童感染该疾病的人数明显多于其他年龄组(36.7%)。男女比例为4:1。致伤动物包括狗(96.7%)、豺狼(1.7%)、猫(0.8%)、猴子(0.4%)和獴(0.4%)。大多数(78.8%)为Ⅲ级暴露。恐水是人类狂犬病的典型特征,95%的病例出现此症状。其余(5%)有动物咬伤史,表现为恐风、畏光,伴有发热、肢体无力、感觉异常和/或麻痹。未接受任何局部伤口处理的人数明显较多(93.4%)。大多数(91.7%)病例从未接受过任何疫苗接种,其余接种不充分;只有5人接受了10 - 14剂神经组织疫苗(NTV),1名面部多处咬伤的儿童接受了5剂NTV、局部伤口处理,并在第3天接受了肌内注射抗狂犬病血清(ARS)。

结果

数据强烈表明,死于狂犬病的人要么未接受任何治疗,要么治疗不当且不充分。因此,有必要对社区和医护人员进行教育,使其了解暴露后立即进行充分治疗的重要性。数据还表明,几十年来该疾病的流行病学情况变化不大。

结论

现有工具可预防该疾病,我们需要做的就是有效实施这些工具。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验