Meyer-Lindenberg A, Wohlfarth K M, Switzer E N
Clinic of Small Animals, School of Veterinary Medicine Hannover, Bischofsholer Damm 15, D-30173 Hannover, Germany.
Aust Vet J. 2003 Oct;81(10):612-4. doi: 10.1111/j.1751-0813.2003.tb12503.x.
A 3-year-old Great Dane with bilateral possible essential blepharospasm resulting in ocular complications is described. Conservative treatment was not successful and the disease was treated with local injections of botulinum toxin A into the orbicularis oculi muscle. Blepharospasm disappeared completely 5 to 6 days after injection and did not reappear until 3 to 4 months later, at which time the injection was repeated. After several treatments over a period of more than 3 years no side effects have occured. Botulinum toxin A appeared to be effective in the treatment of essential blepharospasm in this dog.
本文描述了一只3岁的大丹犬，双侧可能患有原发性眼睑痉挛并导致眼部并发症。保守治疗未成功，遂对其眼轮匝肌局部注射A型肉毒杆菌毒素进行治疗。注射后5至6天，眼睑痉挛完全消失，直至3至4个月后才再次出现，此时重复进行注射。经过3年多的多次治疗，未出现任何副作用。A型肉毒杆菌毒素似乎对治疗该犬的原发性眼睑痉挛有效。
