Kim Myoung-Hee, Kim Mi-Kyung, Choi Bo-Youl, Shin Young-Jeon
Department of Preventive Medicine, Eulji University School of Medicine, Daejeon, Korea.
J Korean Med Sci. 2004 Apr;19(2):195-201. doi: 10.3346/jkms.2004.19.2.195.
This study aimed to estimate nationwide prevalence of the metabolic syndrome and to identify its association with cardiovascular diseases. The data on a national representative sample of 6,147 adults from 1998 Korea National Health and Nutrition Survey were analyzed. The syndrome was determined according to two kinds of modified definition from ATP III, in which abdominal obesity was determined by waist circumference (WC) standard for Asians and waist-to-hip ratio (WHR). Based on the former, prevalence was 22.1% in men and 27.8% in women. However, based on the latter, prevalence was 28.6% and 27.8%, respectively. Although age-specific prevalence was higher in men than in women among the younger group, it became higher in women among the older group because of its steeper rise with age. In multiple logistic regression, the syndrome was found to be positively associated with cardiovascular diseases (adjusted odds ratios (ORs)1.97 by WC and 1.48 by WHR in men, and 1.54 and 1.31 in women). Moreover, its effect size exceeded that of total cholesterol (adjusted ORs 1.21 in men, and 1.08 in women) or LDL cholesterol (1.58 in men and 1.22 in women). It is obvious that the metabolic syndrome prevails in Korea, and its importance regarding cardiovascular diseases is considerable. Prevention strategies should be implemented immediately to avoid cardiovascular epidemic in the near future.
本研究旨在估算全国代谢综合征的患病率,并确定其与心血管疾病的关联。分析了来自1998年韩国国民健康与营养调查的6147名成年人的全国代表性样本数据。根据ATP III的两种修改定义来确定该综合征,其中腹部肥胖通过亚洲人的腰围(WC)标准和腰臀比(WHR)来确定。基于前者,男性患病率为22.1%,女性为27.8%。然而,基于后者,患病率分别为28.6%和27.8%。尽管在较年轻组中按年龄划分的患病率男性高于女性,但在较年长组中女性患病率更高,因为其随年龄增长上升得更快。在多因素逻辑回归分析中,发现该综合征与心血管疾病呈正相关(男性中按WC调整的优势比(OR)为1.97,按WHR调整的为1.48;女性中分别为1.54和1.31)。此外,其效应大小超过了总胆固醇(男性调整后的OR为1.21,女性为1.08)或低密度脂蛋白胆固醇(男性为1.58,女性为1.22)。显然,代谢综合征在韩国普遍存在,且其对心血管疾病的重要性相当大。应立即实施预防策略,以避免在不久的将来出现心血管疾病流行。