Zalutsky M R
Department of Radiology, Duke University Medical Center, PO Box 3808, Durham, NC 27710, USA.
Br J Cancer. 2004 Apr 19;90(8):1469-73. doi: 10.1038/sj.bjc.6601771.
The utility of external beam radiotherapy for the treatment of malignant brain tumours is compromised by the need to avoid excessive radiation damage to normal CNS tissues. This review describes the current status of targeted radiotherapy, an alternative strategy for brain tumour treatment that offers the exciting prospect of increasing the specificity of tumour cell irradiation.
外照射放疗在治疗恶性脑肿瘤时,因需要避免对正常中枢神经系统组织造成过度辐射损伤而受到限制。本综述描述了靶向放疗的现状,这是一种脑肿瘤治疗的替代策略,为提高肿瘤细胞照射的特异性带来了令人兴奋的前景。