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脑肿瘤的靶向放射治疗。

Targeted radiotherapy of brain tumours.

作者信息

Zalutsky M R

机构信息

Department of Radiology, Duke University Medical Center, PO Box 3808, Durham, NC 27710, USA.

出版信息

Br J Cancer. 2004 Apr 19;90(8):1469-73. doi: 10.1038/sj.bjc.6601771.

DOI:10.1038/sj.bjc.6601771
PMID:15083170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2409720/
Abstract

The utility of external beam radiotherapy for the treatment of malignant brain tumours is compromised by the need to avoid excessive radiation damage to normal CNS tissues. This review describes the current status of targeted radiotherapy, an alternative strategy for brain tumour treatment that offers the exciting prospect of increasing the specificity of tumour cell irradiation.

摘要

外照射放疗在治疗恶性脑肿瘤时,因需要避免对正常中枢神经系统组织造成过度辐射损伤而受到限制。本综述描述了靶向放疗的现状,这是一种脑肿瘤治疗的替代策略,为提高肿瘤细胞照射的特异性带来了令人兴奋的前景。

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本文引用的文献

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Vascular targeted endoradiotherapy of tumors using alpha-particle-emitting compounds: theoretical analysis.使用发射α粒子的化合物进行肿瘤的血管靶向内放射治疗:理论分析
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Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials.成人高级别胶质瘤的化疗:来自12项随机试验的个体患者数据的系统评价和荟萃分析。
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