Shepherd James C, Subramanian Aruna, Montgomery Robert A, Samaniego Milagros D, Gong Gary, Bergmann Amy, Blythe David, Dropulic Lesia
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Am J Transplant. 2004 May;4(5):830-3. doi: 10.1111/j.1600-6143.2004.00410.x.
We describe a case of West Nile virus encephalitis in a 54-year-old kidney transplant recipient. The clinical course was rapid and fatal. Serial CSF samples showed an evolving mononuclear pleiocytosis and serial MRIs showed increasing signs of cytotoxic edema in her basal ganglia. Seroepidemiological testing indicated that the infection was most likely acquired from transfusion of fresh frozen plasma at the time of transplantation.
我们描述了一例54岁肾移植受者感染西尼罗河病毒脑炎的病例。临床病程进展迅速且致命。连续的脑脊液样本显示单核细胞增多症不断演变，连续的磁共振成像显示其基底神经节细胞毒性水肿的迹象不断增加。血清流行病学检测表明，感染很可能是在移植时输注新鲜冷冻血浆所致。
