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西尼罗河病毒特异性抗体在病毒血症献血者中的持续存在情况。

Persistence of West Nile virus-specific antibodies in viremic blood donors.

作者信息

Prince Harry E, Tobler Leslie H, Yeh Cindy, Gefter Nelly, Custer Brian, Busch Michael P

机构信息

Focus Diagnostics, Cypress, California, USA.

出版信息

Clin Vaccine Immunol. 2007 Sep;14(9):1228-30. doi: 10.1128/CVI.00233-07. Epub 2007 Jul 25.

Abstract

We evaluated West Nile virus (WNV) antibody persistence by using follow-up plasma samples from 35 blood donors who made viremic donations in 2005. At 26 to 34 days of follow-up, all of the donors (n = 33) were positive for WNV immunoglobulin M (IgM), IgA, and IgG. At 1-year of follow-up, 17% of the donors (n = 23) were positive for WNV IgM, 57% were positive for WNV IgA, and 100% were positive for WNV IgG.

摘要

我们通过使用2005年出现病毒血症的35名献血者的随访血浆样本,评估了西尼罗河病毒(WNV)抗体的持久性。在随访的26至34天,所有献血者(n = 33)的WNV免疫球蛋白M(IgM)、IgA和IgG均呈阳性。在随访1年时,17%的献血者(n = 23)WNV IgM呈阳性,57%的献血者WNV IgA呈阳性,100%的献血者WNV IgG呈阳性。

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