1989 - 1990年奥克兰的绒毛取样
Chorionic villus sampling in Auckland 1989-90.
作者信息
Birdsall M, Roberts A B, Fisher R, Beecroft D, Bailey R
机构信息
Department of Obstetrics, Auckland University School of Medicine, National Women's Hospital.
出版信息
N Z Med J. 1992 Aug 26;105(940):332-3.
AIMS
to perform an audit of all 197 chorionic villus sampling procedures performed in Auckland in 1989-90.
METHOD
an attempt to trace the outcome in all 197 cases and this was possible in 188 cases.
RESULTS
89% of chorionic villus samples were performed transvaginally and 11% transabdominally. The total fetal loss rate was 9.6% (18) with six spontaneous miscarriages before 20 weeks gestation (3.2%), one intermediate fetal death and one neonatal death. There were 10 elective terminations of pregnancy following abnormal results so the spontaneous loss rate was 4.3%.
CONCLUSIONS
the loss rate was lower than that reported in the European and Canadian multicentre trials. The sampling success rate, however, was poor with 13.7% failed procedures. This improved in the second year of the service to 10%. There were no failure cultures or examples of mosaicism.
目的
对1989 - 1990年在奥克兰进行的197例绒毛取样操作进行审查。
方法
试图追踪所有197例病例的结果，其中188例得以追踪。
结果
89%的绒毛取样经阴道进行，11%经腹进行。胎儿总丢失率为9.6%（18例），其中妊娠20周前有6例自然流产（3.2%），1例中期胎儿死亡和1例新生儿死亡。因结果异常有10例选择性终止妊娠，所以自然丢失率为4.3%。
结论
丢失率低于欧洲和加拿大多中心试验报告的水平。然而，取样成功率较低，有13.7%的操作失败。在服务的第二年这一比例提高到了10%。没有培养失败或嵌合体的例子。
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