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Free radical production by dysfunctional eNOS.

作者信息

Verhaar M C, Westerweel P E, van Zonneveld A J, Rabelink T J

机构信息

Department of Vascular Medicine, University Medical Center Utrecht, The Netherlands.

出版信息

Heart. 2004 May;90(5):494-5. doi: 10.1136/hrt.2003.029405.

DOI:10.1136/hrt.2003.029405
PMID:15084540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1768213/
Abstract
摘要

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本文引用的文献

1
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension.四氢生物蝶呤的氧化导致高血压中内皮细胞一氧化氮合酶的解偶联。
J Clin Invest. 2003 Apr;111(8):1201-9. doi: 10.1172/JCI14172.
2
Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase.过氧亚硝酸盐、四氢生物蝶呤、抗坏血酸和硫醇的相互作用:对内皮型一氧化氮合酶解偶联的影响。
J Biol Chem. 2003 Jun 20;278(25):22546-54. doi: 10.1074/jbc.M302227200. Epub 2003 Apr 10.
3
HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells.HMG-CoA还原酶抑制剂可增加血管内皮细胞中GTP环化水解酶I的mRNA及四氢生物蝶呤水平。
Arterioscler Thromb Vasc Biol. 2003 Feb 1;23(2):176-82. doi: 10.1161/01.atv.0000054659.72231.a1.
4
Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity.长期维生素C治疗可提高血管四氢生物蝶呤水平和一氧化氮合酶活性。
Circ Res. 2003 Jan 10;92(1):88-95. doi: 10.1161/01.res.0000049166.33035.62.
5
Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice.内皮型一氧化氮合酶的过表达加速了载脂蛋白E缺乏小鼠动脉粥样硬化病变的形成。
J Clin Invest. 2002 Aug;110(3):331-40. doi: 10.1172/JCI15215.
6
Paradoxical reduction of fatty streak formation in mice lacking endothelial nitric oxide synthase.内皮型一氧化氮合酶缺乏的小鼠中脂肪条纹形成的反常减少
Circulation. 2002 Apr 30;105(17):2078-82. doi: 10.1161/01.cir.0000015853.59427.32.
7
The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study.四氢生物蝶呤与氧化型四氢生物蝶呤类似物的比例控制内皮型一氧化氮合酶释放超氧化物:一项电子顺磁共振自旋捕获研究。
Biochem J. 2002 Mar 15;362(Pt 3):733-9. doi: 10.1042/0264-6021:3620733.
8
Folates and cardiovascular disease.叶酸与心血管疾病
Arterioscler Thromb Vasc Biol. 2002 Jan;22(1):6-13. doi: 10.1161/hq0102.102190.
9
Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress.心血管疾病中的内皮功能障碍:氧化应激的作用
Circ Res. 2000 Nov 10;87(10):840-4. doi: 10.1161/01.res.87.10.840.
10
L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin.L-抗坏血酸通过四氢生物蝶呤的化学稳定作用增强内皮型一氧化氮的合成。
J Biol Chem. 2001 Jan 5;276(1):40-7. doi: 10.1074/jbc.M004392200.