Seeto R, Ng S, McClellan K A, Billson F A
Department of Ophthalmology, University of Sydney, Australia.
Ophthalmic Surg. 1992 Aug;23(8):538-44.
We compared the performance of 10-0 Novafil (polybutester, Davis & Geck, American Cyanamid Company, New South Wales, Australia.) with that of 10-0 nylon (Alcon) in 60 patients undergoing extracapsular cataract extraction and implantation of a posterior chamber intraocular lens. A standard technique was used, and the incision was closed with interrupted sutures of either 10-0 Novafil or 10-0 nylon. Length of follow up ranged from 6 to 26 months (average, 15 months). We assessed the intraoperative handling qualities of the suture materials, as well as their effect on wound healing and inflammation. We also compared the surgically-induced astigmatism in the two suture groups over the first 3 postoperative months and then in long-term follow up (average, 15 months). Sutures removed at long-term follow up were examined by scanning electron microscopy (SEM). Both suture materials handled easily at operation and were well tolerated by all patients. There was no significantly different surgically-induced astigmatism in the two suture groups after 12 weeks (P = .962) or during longer follow up (P = .401). SEM confirmed more advanced biodegradation of nylon as compared with Novafil sutures after they had been in place an average of 18 months.
我们比较了10-0诺瓦菲尔缝线（聚丁酯，戴维斯&盖克公司，美国氰胺公司，澳大利亚新南威尔士州）与10-0尼龙缝线（爱尔康公司）在60例行囊外白内障摘除及后房型人工晶状体植入术患者中的性能。采用标准技术，用10-0诺瓦菲尔缝线或10-0尼龙缝线间断缝合关闭切口。随访时间为6至26个月（平均15个月）。我们评估了缝线材料的术中操作特性，以及它们对伤口愈合和炎症的影响。我们还比较了两组缝线在术后前3个月以及长期随访（平均15个月）期间手术引起的散光情况。对长期随访时拆除的缝线进行扫描电子显微镜（SEM）检查。两种缝线在手术中操作均简便，所有患者耐受性良好。两组缝线在12周后（P = 0.962）或更长时间随访期间（P = 0.401）手术引起的散光无显著差异。扫描电子显微镜检查证实，平均植入18个月后，尼龙缝线的生物降解程度比诺瓦菲尔缝线更明显。
