Gimbel H V, Raanan M G, DeLuca M
Gimbel Eye Centre, Calgary, Alberta, Canada.
J Cataract Refract Surg. 1992 Jan;18(1):42-50. doi: 10.1016/s0886-3350(13)80382-3.
Two hundred patients were enrolled in a randomized, prospective clinical trial comparing the use of 10-0 nylon, 10-0 polypropylene (Prolene), 11-0 polyester (Mersilene), and 10-0 polyethylene (Novafil) suture materials on the amount and decay curves of surgically induced astigmatism following intraocular lens (IOL) surgery. Patients with Mersilene and nylon sutures had the highest amounts of induced with-the-rule (WTR) cylinder (significantly more than Prolene) at one day after surgery. However, the WTR cylinder decayed rapidly for nylon during the first three months but more slowly for Mersilene because of its lack of stretchability. The Prolene group had the lowest level of induced WTR cylinder at one day, but against-the-rule (ATR) drift occurred, leaving cases with ATR astigmatism by a year. The nylon group had the second highest amount of induced WTR cylinder at one day, which had decayed to ATR cylinder by five months. Between one and two years postoperatively, the nylon group experienced a significant ATR shift. The amount of early induced WTR cylinder seemed to be related to the knot-tying technique and tissue gripping characteristics, whereas the shape of the decay curve was related to the material characteristics of the suture.
200名患者参与了一项随机、前瞻性临床试验，该试验比较了10-0尼龙线、10-0聚丙烯线（普理灵）、11-0聚酯线（爱惜康）和10-0聚乙烯线（诺菲）在人工晶状体（IOL）手术后手术诱导散光的量和衰减曲线上的应用。使用爱惜康和尼龙缝线的患者在术后一天诱导的顺规（WTR）柱镜量最高（显著高于普理灵）。然而，尼龙缝线的WTR柱镜在前三个月迅速衰减，而爱惜康的衰减较慢，因为它缺乏拉伸性。普理灵组在术后一天诱导的WTR柱镜水平最低，但出现了逆规（ATR）漂移，到一年时出现了ATR散光病例。尼龙组在术后一天诱导的WTR柱镜量第二高，到五个月时已衰减为ATR柱镜。术后一到两年间，尼龙组出现了显著的ATR偏移。早期诱导的WTR柱镜量似乎与打结技术和组织夹持特性有关，而衰减曲线的形状与缝线的材料特性有关。
