Cravy T V
J Cataract Refract Surg. 1989 Jan;15(1):61-9. doi: 10.1016/s0886-3350(89)80142-7.
The long-term decay of surgically induced corneal astigmatism following planned extracapsular cataract extraction has been studied in 395 patients who had limbal or scleral pocket incisions of 60 to 140 degrees. Limbal incisions were closed with a full-thickness shoelace closure; scleral pocket incisions, with a new, modified shoelace closure. Suture material was 10-0 nylon, 9-0 nylon, 10-0 polypropylene (Prolene), and 10-0 polyester (Mersilene). The nylon sutures demonstrated clinically significant hydrolysis beginning at five months (10-0) and 12 months (9-0). Because of the adverse hydrolytic effects, 10-0 nylon was eliminated from the scleral pocket closure group. The hydrolysis of 9-0 nylon caused excessive late astigmatic changes in patients who did not heal normally. Prolene and Mersilene showed no tendency toward hydrolysis; however, the elasticity of Prolene produced more against-the-rule change in astigmatism than desired even though it was stable over the long run. I stopped using nylon sutures in cataract (and keratoplasty) wound closures and switched to routine use of Mersilene.
对395例行计划内囊外白内障摘除术且角膜缘或巩膜隧道切口为60至140度的患者，研究了手术引起的角膜散光的长期衰减情况。角膜缘切口采用全层鞋带式缝合关闭；巩膜隧道切口采用一种新的改良鞋带式缝合关闭。缝合材料为10-0尼龙线、9-0尼龙线、10-0聚丙烯（普理灵）和10-0聚酯（慕丝线）。尼龙缝线在5个月（10-0）和12个月（9-0）时出现具有临床意义的水解。由于水解的不良影响，10-0尼龙线被从巩膜隧道切口缝合组中剔除。9-0尼龙线的水解在愈合不正常的患者中导致了过度的晚期散光变化。普理灵和慕丝线没有水解倾向；然而，尽管普理灵长期来看是稳定的，但其弹性导致散光出现了比预期更多的逆规变化。我不再在白内障（和角膜移植术）伤口缝合中使用尼龙缝线，转而常规使用慕丝线。
