Ikeda Yoichi, Saku Motonori, Kawanaka Hirofumi, Muranaka Toru, Takeshita Morishige, Watanabe Jiro, Yoshida Kohji, Sugimachi Keizo
Department of Surgery and Clinical Research Institute, National Kyushu Medical Center, Fukuoka, Japan.
Hepatogastroenterology. 2004 Mar-Apr;51(56):443-6.
BACKGROUND/AIMS: Synchronous and metachronous multiple colorectal cancers are not rare occurrences. Since features of colorectal cancer depend on tumor location, we focused attention on the tumor distribution of synchronous and meta-chronous lesions in colorectal cancer.
The records of 1812 patients with colorectal malignancies (either invasive colorectal cancer or high grade dysplasia) were clinicopathologically analyzed.
In one hundred and twenty patients with colorectal malignancies there were synchronous or metachronous lesions. The distribution of synchronous malignancies showed a significant shift from the proximal to the distal site, while in metachronous malignancies, the distribution of second tumors showed a significant shift from the distal to the proximal site.
Our findings suggest that different types of cancer lesions do exist, hence careful and meticulous examinations are important.
背景/目的:同时性和异时性多发性结直肠癌并非罕见。由于结直肠癌的特征取决于肿瘤位置,我们将注意力集中在结直肠癌同时性和异时性病变的肿瘤分布上。
对1812例结直肠恶性肿瘤(浸润性结直肠癌或高级别发育异常)患者的记录进行临床病理分析。
120例结直肠恶性肿瘤患者存在同时性或异时性病变。同时性恶性肿瘤的分布显示出从近端部位向远端部位的显著转移,而异时性恶性肿瘤中,第二肿瘤的分布显示出从远端部位向近端部位的显著转移。
我们的研究结果表明确实存在不同类型的癌性病变,因此仔细和细致的检查很重要。