Hirose Y, Hamada S, Imakita S, Naito H, Nakanishi T, Kaminaga T, Takamiya M
Department of Radiology, Osaka University Medical School.
Nihon Igaku Hoshasen Gakkai Zasshi. 1992 May 25;52(5):571-5.
To evaluate the growth rate of abdominal aortic aneurysms, sequential computed tomography (CT) examinations were performed on 125 nonoperated patients (M/F 101/24, mean age 67 +/- 8 years, 129 lesions) at intervals of at least 6 months. Growth rates of aneurysms were obtained by subtracting the first from the last diameter and adjusting for examination interval. Mean growth rate was 0.28 +/- 0.26 cm/year. Aneurysms with an initial diameter exceeding 4 or 5 cm showed significantly faster growth than smaller aneurysms. There was no significant correlation between growth rate and atherosclerogenic factors, but systolic blood pressure was significantly higher in patients whose aneurysms ruptured. Our study showed quantitatively that aneurysms with a large diameter have a rapid growth rate, the growth rate of infrarenal aneurysms is significantly faster than that of suprarenal aneurysms, and blood pressure control is important to prevent rupture.
为评估腹主动脉瘤的生长速率，对125例未接受手术治疗的患者（男性101例，女性24例，平均年龄67±8岁，共129个病灶）进行了序贯计算机断层扫描（CT）检查，检查间隔至少为6个月。通过用末次直径减去首次直径并根据检查间隔进行调整来得出动脉瘤的生长速率。平均生长速率为0.28±0.26厘米/年。初始直径超过4厘米或5厘米的动脉瘤比小动脉瘤生长明显更快。生长速率与动脉粥样硬化形成因素之间无显著相关性，但动脉瘤破裂患者的收缩压显著更高。我们的研究定量显示，大直径动脉瘤生长速率快，肾下腹主动脉瘤的生长速率明显快于肾上腹主动脉瘤，且控制血压对预防破裂很重要。
