Nystedt Astrid, Edvardsson David, Willman Ania
Obstetrics and Gynaecology, Department of Clinical Science, Umeå University, Umeå, Sweden.
J Clin Nurs. 2004 May;13(4):455-66. doi: 10.1046/j.1365-2702.2003.00849.x.
Clinical ambiguity concerning effects of epidural analgesia for pain relief in labour seems to reflect a need for evidence-based knowledge for midwives.
This study aimed to review, with a systematic approach, the literature about effects and risks associated with the use of epidural analgesia for pain relief in labour and childbirth.
A structured question was formulated and used for deriving search terms, establishing the inclusion of certain criteria and retrieving articles, i.e. what are the effects of epidural analgesia for pain relief in labour and childbirth? References were obtained through searches using MeSH-terms in Medline and Subheadings (SH) in CINAHL (e.g. Obstetrical Analgesia combined either with psychology or adverse effects and together with, Dystocia, Caesarean Section, Infant Newborn and Breastfeeding). The articles were divided into prospective randomized trials (C), non-randomized prospective studies (P) and retrospective studies (R). Scientific quality of the studies was assessed on a three-grade scale: high scientific quality (I), moderate scientific quality (II) or low scientific quality (III).
Twenty-four articles were retrieved and systematically assessed. Seven studies were judged as high quality, 15 as moderate quality and two as low quality. The majority of studies appraised in this review failed to obtain or establish a cause and effect relationship. According to the data, it seems clear that the use of epidural analgesia is considered to be an effective method of pain relief during labour and childbirth from the perspective of women giving birth.
Midwives and doctors can recommend this form of pain relief. However, information about possible associations with adverse effects in mothers and infants must be provided to expectant couples.
硬膜外镇痛用于分娩镇痛的临床效果存在不确定性,这似乎反映出助产士需要基于证据的知识。
本研究旨在采用系统的方法,回顾有关硬膜外镇痛用于分娩和分娩镇痛的效果及风险的文献。
制定了一个结构化问题,用于推导检索词、确定纳入标准和检索文章,即硬膜外镇痛用于分娩和分娩镇痛的效果如何?通过在Medline中使用医学主题词(MeSH)和在CINAHL中使用副标题(SH)进行检索获得参考文献(例如,产科镇痛与心理学或不良反应结合,以及难产、剖宫产、新生儿和母乳喂养)。文章分为前瞻性随机试验(C)、非随机前瞻性研究(P)和回顾性研究(R)。研究的科学质量按三级量表进行评估:高科学质量(I)、中等科学质量(II)或低科学质量(III)。
检索到24篇文章并进行了系统评估。7项研究被判定为高质量,15项为中等质量,2项为低质量。本综述中评估的大多数研究未能获得或确立因果关系。根据数据,从分娩女性的角度来看,硬膜外镇痛的使用似乎显然被认为是分娩和分娩期间有效的镇痛方法。
助产士和医生可以推荐这种镇痛方式。然而,必须向准父母提供有关与母婴不良反应可能关联的信息。