Ghaemmaghami F, Modares M, Behtash N, Moosavi A Z
Department of Gynecology-Oncology, Tehran University of Medical Sciences, Vali-e-Asr Hospital, Imam Khomeini Hospital Complex, Keshavarz Boulevard, Tehran 14194, Iran.
Int J Gynecol Cancer. 2004 Mar-Apr;14(2):384-7. doi: 10.1111/j.1048-891x.2004.014227.x.
Cutaneous metastases of vulvar carcinoma are extremely rare and have been reported in six patients so far. Our patient, who is the seventh one, is a 38-year-old woman with a history of diabetes mellitus. After detecting stage III squamous cell carcinoma of the vulva, she underwent radical vulvectomy and bilateral inguinal lymphadenectomy. She received 6000 cGy external beam radiation for positive margins. Six months later, she came back with multiple advanced skin lesions. Biopsy was performed and lesions were confirmed as cutaneous metastases. For her palliation, some chemotherapy drugs were prescribed. She is on her sixth chemotherapy cycle, but these skin lesions are somewhat a preterminal event and there is no well-established treatment for this phase of disease.
外阴癌的皮肤转移极为罕见，迄今为止仅有6例相关报道。我们的患者是第7例，为一名38岁的糖尿病女性。在检测出外阴III期鳞状细胞癌后，她接受了根治性外阴切除术和双侧腹股沟淋巴结切除术。因切缘阳性，她接受了6000 cGy的体外照射。6个月后，她因多处进展性皮肤病变前来复诊。进行了活检，病变被确诊为皮肤转移。为缓解症状，给她开了一些化疗药物。她正在进行第六个化疗周期，但这些皮肤病变在某种程度上是终末期事件，对于疾病的这个阶段尚无成熟的治疗方法。
