Tobias D H, Smith H O, Jones J G, Anderson P, Runowicz C D, Goldberg G L
Department of Obstetrics and Gynecology, Albert Einstein College of Medicine, Bronx, New York, USA.
Eur J Gynaecol Oncol. 1995;16(5):382-6.
Cancer of the vulva, the fourth most common malignancy of the female genital tract, accounts for approximately 4% of all gynecologic malignancies. Only one prior case of a cutaneous metastasis from a vulvar cancer has been previously reported and involved a FIGO Stage III (T2N1M0) lesion. We report a patient with Stage II (T2N0M0) vulvar carcinoma who developed cutaneous metastases. This case demonstrates the ability of vulvar carcinoma to disseminate hematogenously, despite complete surgical resection with negative skin margins, and negative lymph nodes. In addition, this case emphasizes the importance of careful and close follow-up of all patients with vulvar carcinoma.
外阴癌是女性生殖道第四大常见恶性肿瘤,约占所有妇科恶性肿瘤的4%。此前仅报道过1例外阴癌皮肤转移的病例,该病例为国际妇产科联盟(FIGO)III期(T2N1M0)病变。我们报告1例II期(T2N0M0)外阴癌发生皮肤转移的患者。该病例表明,尽管手术切除彻底,切缘皮肤及淋巴结均为阴性,但外阴癌仍有血行播散的可能。此外,该病例强调了对所有外阴癌患者进行仔细密切随访的重要性。