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心血管疾病患者焦虑和抑郁障碍的治疗

Treatment of anxiety and depressive disorders in patients with cardiovascular disease.

作者信息

Davies Simon J C, Jackson Peter R, Potokar John, Nutt David J

机构信息

Psychopharmacology Unit, Dorothy Hodgkin Building, Bristol BS1 3NY.

出版信息

BMJ. 2004 Apr 17;328(7445):939-43. doi: 10.1136/bmj.328.7445.939.

DOI:10.1136/bmj.328.7445.939
PMID:15087342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC390215/
Abstract

What role do selective serotonin reuptake inhibitors have in treating psychiatric morbidity in patients with cardiovascular disease? This review discusses the safety and efficacy of various antidepressants in this group of patients and their potential for improving cardiovascular outcomes

摘要

选择性5-羟色胺再摄取抑制剂在治疗心血管疾病患者的精神疾病方面发挥着什么作用？这篇综述讨论了各类抗抑郁药在这类患者中的安全性和疗效，以及它们改善心血管疾病预后的潜力。

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本文引用的文献

1
Mortality and poststroke depression: a placebo-controlled trial of antidepressants.死亡率与中风后抑郁：抗抑郁药的一项安慰剂对照试验
Am J Psychiatry. 2003 Oct;160(10):1823-9. doi: 10.1176/appi.ajp.160.10.1823.
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Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy.急性冠脉事件后接受选择性5-羟色胺再摄取抑制剂舍曲林治疗的抑郁症患者的血小板/内皮生物标志物：舍曲林抗抑郁药心脏病发作随机试验（SADHART）血小板亚研究
Circulation. 2003 Aug 26;108(8):939-44. doi: 10.1161/01.CIR.0000085163.21752.0A. Epub 2003 Aug 11.
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Treatment of depression in patients with heart disease.
Biol Psychiatry. 2003 Aug 1;54(3):262-8. doi: 10.1016/s0006-3223(03)00320-2.
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Depression and cardiovascular disease: mechanisms of interaction.抑郁症与心血管疾病：相互作用机制
Biol Psychiatry. 2003 Aug 1;54(3):248-61. doi: 10.1016/s0006-3223(03)00568-7.
5
Effect of antidepressants and their relative affinity for the serotonin transporter on the risk of myocardial infarction.抗抑郁药及其对5-羟色胺转运体的相对亲和力对心肌梗死风险的影响。
Circulation. 2003 Jul 8;108(1):32-6. doi: 10.1161/01.CIR.0000079172.43229.CD. Epub 2003 Jun 23.
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Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial.治疗抑郁症和低感知社会支持对心肌梗死后临床事件的影响：冠心病患者强化康复（ENRICHD）随机试验。
JAMA. 2003 Jun 18;289(23):3106-16. doi: 10.1001/jama.289.23.3106.
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A double-blind, placebo-controlled study of sertraline in the prevention of depression in stroke patients.舍曲林预防中风患者抑郁的双盲、安慰剂对照研究。
Psychosomatics. 2003 May-Jun;44(3):216-21. doi: 10.1176/appi.psy.44.3.216.
8
Early fluoxetine treatment of post-stroke depression--a three-month double-blind placebo-controlled study with an open-label long-term follow up.中风后抑郁症的早期氟西汀治疗——一项为期三个月的双盲安慰剂对照研究及开放标签长期随访
J Neurol. 2003 Mar;250(3):347-51. doi: 10.1007/s00415-003-1014-3.
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Drug intolerance due to nonspecific adverse effects related to psychiatric morbidity in hypertensive patients.
Arch Intern Med. 2003 Mar 10;163(5):592-600. doi: 10.1001/archinte.163.5.592.
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Increased frequency of cytochrome P450 2D6 poor metabolizers among patients with metoprolol-associated adverse effects.美托洛尔相关不良反应患者中细胞色素P450 2D6慢代谢者的频率增加。
Clin Pharmacol Ther. 2002 Oct;72(4):429-37. doi: 10.1067/mcp.2002.127111.