Angiolillo Anne, Luban Naomi L C
George Washington University School of Medicine and Children's National Medical Center, Washington, DC 20010, USA.
J Pediatr Hematol Oncol. 2004 Apr;26(4):267-9. doi: 10.1097/00043426-200404000-00012.
This article describes an 8-month-old boy with Langerhans cell histiocytosis and A-positive blood group who developed a febrile hemolytic transfusion reaction with hepatic and renal failure leading to his death secondary to hemolysis from an out-of-group platelet transfusion from an O-positive donor. High-titer anti-A antibody caused the hemolysis. Volume reduction of out-of-group platelets should be considered, particularly when single-donor platelet pheresis platelets are used in children with small plasma volumes.
本文描述了一名8个月大的患有朗格汉斯细胞组织细胞增多症且血型为A阳性的男孩，他因接受了一名O阳性供者的血型不匹配的血小板输注而发生溶血，继发高热性溶血性输血反应，并伴有肝肾功能衰竭，最终导致死亡。高滴度的抗A抗体引起了溶血。应考虑减少血型不匹配血小板的输注量，尤其是当单采血小板用于血浆量少的儿童时。
