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老年人群中低级别动脉瘤性蛛网膜下腔出血的血管内治疗

Endovascular management of poor-grade aneurysmal subarachnoid hemorrhage in the geriatric population.

作者信息

Jain Rajan, Deveikis John, Thompson Byron Gregory

机构信息

Department of Radiology, University of Michigan Hospitals, Ann Arbor, USA.

出版信息

AJNR Am J Neuroradiol. 2004 Apr;25(4):596-600.

Abstract

BACKGROUND AND PURPOSE

The incidence of poor-grade (Hunt and Hess grade IV and V) subarachnoid hemorrhage (SAH) is higher in elderly patients (>70 years) than in younger groups. The aim of this retrospective study was to analyze the outcome of these poor grade elderly patients after endovascular treatment.

METHODS

We retrospectively reviewed the clinical records of 27 patients older than 70 years who underwent endovascular treatment for aneurysmal SAH between January 1996 and July 2002. Thirteen patients with SAH and a poor Hunt and Hess grade at initial presentation had been treated by endovascular means. Their outcomes were assessed by the using the Glasgow Outcome Scale (GOS).

RESULTS

Two patients (15%) had a good outcome according to the GOS. Three patients (23%) were moderately disabled, two (15%) were severely disabled at the time of discharge from the hospital, and six (47%) died. Five patients (38%) developed clinical vasospasm and underwent balloon angioplasty. Three procedure-related deaths occurred (23%).

CONCLUSION

Endovascular treatment has modified the management of poor-grade SAH in elderly patients, most of whom are high-risk surgical candidates. Endovascular treatment can be administered early after the initial ictus, reducing the risk of rebleeding and providing an option to pursue aggressive triple-H therapy. Symptomatic vasospasm can also be treated by endovascular means in the initial setting.

摘要

背景与目的

老年患者(>70岁)中,低分级(Hunt和Hess分级IV级和V级)蛛网膜下腔出血(SAH)的发生率高于年轻组。这项回顾性研究的目的是分析这些低分级老年患者接受血管内治疗后的结局。

方法

我们回顾性分析了1996年1月至2002年7月间27例年龄大于70岁、因动脉瘤性SAH接受血管内治疗患者的临床记录。13例初次就诊时Hunt和Hess分级较低的SAH患者接受了血管内治疗。采用格拉斯哥预后量表(GOS)评估其结局。

结果

根据GOS,2例患者(15%)预后良好。3例患者(23%)中度残疾,2例(15%)出院时严重残疾,6例(47%)死亡。5例患者(38%)发生临床血管痉挛并接受了球囊血管成形术。发生3例与手术相关的死亡(23%)。

结论

血管内治疗改变了老年低分级SAH患者的治疗方式,这些患者大多是手术高风险候选者。血管内治疗可在发病初期尽早进行,降低再出血风险,并为积极进行“三高”治疗提供了一种选择。有症状的血管痉挛在初始阶段也可通过血管内方法治疗。

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