Nishimura K, Kitaichi M, Izumi T, Itoh H
Chest Disease Research Institute, Kyoto University, Japan.
Radiology. 1992 Sep;184(3):779-85. doi: 10.1148/radiology.184.3.1509067.
Diffuse panbronchiolitis (DPB) is characterized by chronic airflow limitation and airway inflammation with bronchiolar lesions. Chest radiographs of patients with DPB usually show small nodular shadows throughout both lungs. The authors investigated the nature and pathogenesis of the radiologic features of DPB by correlating high-resolution computed tomographic (HRCT) findings with histopathologic features. The HRCT images of nine patients with DPB were compared with the observations made with inflated lung specimens. The HRCT findings of DPB included centrilobularly distributed, small rounded areas of attenuation; branched linear areas of attenuation, contiguous with the small rounded areas; dilated airways with thick walls, also common outside secondary pulmonary lobules; and decreased lung attenuation in peripheral areas due to air trapping caused by bronchiolar narrowing in the subpleural zones. The authors believe that HRCT best demonstrates this characteristic location of small rounded areas of attenuation associated with dilated airways.
弥漫性泛细支气管炎（DPB）的特征为慢性气流受限以及伴有细支气管病变的气道炎症。DPB患者的胸部X线片通常显示两肺布满小结节状阴影。作者通过将高分辨率计算机断层扫描（HRCT）结果与组织病理学特征相关联，研究了DPB放射学特征的性质和发病机制。将9例DPB患者的HRCT图像与充气肺标本的观察结果进行了比较。DPB的HRCT表现包括小叶中心分布的小圆形低密度区；与小圆形区域相连的分支状线性低密度区；壁增厚的扩张气道，在次级肺小叶外也常见；以及由于胸膜下区细支气管狭窄导致空气潴留引起的周边区域肺密度减低。作者认为HRCT最能显示与扩张气道相关的小圆形低密度区的这一特征性位置。
