Knutson Tomas
Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Curr Opin Urol. 2004 Jan;14(1):35-9. doi: 10.1097/00042307-200401000-00008.
Endoprosthesis has been used to maintain luminal patency in several different diseases and is well established in cardiovascular and gastrointestinal pathologies. The usefulness and application in prostatic pathology and benign prostatic hyperplasia are not as clear. This report reviews the development of overactive bladder in patients with bladder outlet obstruction due to benign prostatic hyperplasia. It also describes a new application of prostatic stents in patients with combined overactive bladder and bladder outlet obstruction.
Over the last few decades, interest has been focused on the pathology of overactive bladder due to bladder outlet obstruction. Persistent outlet obstruction can certainly induce overactivity in some cases. However, the significance of preoperative identification of the latter problem is still an open issue, and it is obviously of vital importance to find instruments to identify parameters of prognostic significance. Different prostatic stents have been used for a variety of purposes. Recent studies have demonstrated that prostatic stents are effective in relieving obstruction and urinary retention. However, the role of prostatic stents in bladder outlet obstruction is still not clear when compared with other minimally invasive options. By using a prostatic stent to simulate transurethral resection of the prostate, the risk of post-resection incontinence in patients with combined severe bladder outlet obstruction and severe overactive bladder has been possible to assess before the operation. However, larger controlled clinical studies are needed to corroborate the value of the test.
Prostatic obstruction can induce severe overactive bladder in some cases. A prostatic stent to relieve outflow obstruction and to simulate transurethral resection of the prostate decreases the risk of post-resection incontinence in patients with combined severe bladder outlet obstruction and severe overactive bladder because very high risk patients can be excluded from surgery. The stent test indicates that patients who do not leak and experience reduced symptoms when they are relieved of their outlet obstruction can be advised to have a transurethral resection of the prostate.
腔内修复术已被用于维持多种不同疾病的管腔通畅,在心血管和胃肠道疾病中已得到充分确立。其在前列腺疾病和良性前列腺增生中的实用性及应用尚不清楚。本报告回顾了良性前列腺增生导致膀胱出口梗阻患者膀胱过度活动症的发展情况。还描述了前列腺支架在合并膀胱过度活动症和膀胱出口梗阻患者中的新应用。
在过去几十年中,人们的兴趣集中在膀胱出口梗阻导致的膀胱过度活动症的病理上。持续的出口梗阻在某些情况下肯定会诱发膀胱过度活动。然而,术前识别后一个问题的意义仍然是一个悬而未决的问题,找到能够识别具有预后意义参数的工具显然至关重要。不同的前列腺支架已被用于多种目的。最近的研究表明,前列腺支架在缓解梗阻和尿潴留方面是有效的。然而,与其他微创选择相比,前列腺支架在膀胱出口梗阻中的作用仍不明确。通过使用前列腺支架模拟经尿道前列腺切除术,可以在手术前评估合并严重膀胱出口梗阻和严重膀胱过度活动症患者术后尿失禁的风险。然而,需要更大规模的对照临床研究来证实该测试的价值。
前列腺梗阻在某些情况下可诱发严重的膀胱过度活动症。一种用于缓解流出道梗阻并模拟经尿道前列腺切除术的前列腺支架,可降低合并严重膀胱出口梗阻和严重膀胱过度活动症患者术后尿失禁的风险,因为可以将极高风险的患者排除在手术之外。支架测试表明,对于那些解除出口梗阻后不漏尿且症状减轻的患者,可以建议其进行经尿道前列腺切除术。