Sreedevi P, Sivaramakrishna B, Suresh A, Radhakrishnaiah K
Department of Zoology, Sri Krishnadevaraya University, Anantapur-515 003, A.P., India.
Environ Pollut. 1992;77(1):59-63. doi: 10.1016/0269-7491(92)90158-7.
Nickel has an adverse effect on some aspects of protein metabolism of the freshwater fish, Cyprinus carpio. The main changes observed were: (a) Decrease in soluble, structural and total proteins, AlAT and AAT activities with an increase in the levels of free amino acids, protease and GDH activities and ammonia in the gill and kidney at 1, 2, 3, and 4 days of exposure to a lethal concentration, 40 mg litre(-1) of nickel; (b) Increase in soluble, structural and total proteins, free amino acids and the activities of protease, AlAT, AAT and GDH with a decrease in ammonia and urea in these organs at 1, 5, 10 and 15 days of exposure to sublethal concentration, 8 mg litre(-1); (c) The magnitude in these changes increased over time with both concentrations of the metal, and was more marked in gill than in kidney.
镍对淡水鱼鲤鱼的蛋白质代谢的某些方面具有不利影响。观察到的主要变化如下：(a) 在暴露于致死浓度（40毫克/升镍）1、2、3和4天时，鳃和肾脏中的可溶性蛋白、结构蛋白和总蛋白、谷丙转氨酶（AlAT）和谷草转氨酶（AAT）活性下降，同时游离氨基酸、蛋白酶和谷氨酸脱氢酶（GDH）活性以及氨水平升高；(b) 在暴露于亚致死浓度（8毫克/升）1、5、10和15天时，这些器官中的可溶性蛋白、结构蛋白和总蛋白、游离氨基酸以及蛋白酶、AlAT、AAT和GDH活性增加，同时氨和尿素减少；(c) 随着金属两种浓度的增加，这些变化的幅度随时间增加，并且在鳃中比在肾脏中更明显。
