Yu Jiujiang, Bhatnagar Deepak, Cleveland Thomas E
U.S. Department of Agriculture, Agricultural Research Service, Southern Regional Research Center, 1100 Robert E. Lee Boulevard, New Orleans, LA 70124, USA.
FEBS Lett. 2004 Apr 23;564(1-2):126-30. doi: 10.1016/S0014-5793(04)00327-8.
An 82-kb Aspergillus parasiticus genomic DNA region representing the completed sequence of the well-organized aflatoxin pathway gene cluster has been sequenced and annotated. In addition to the 19 reported and characterized aflatoxin pathway genes and the four sugar utilization genes in this cluster, we report here the identification of six newly identified genes which are putatively involved in aflatoxin formation. The function of these genes, the cluster organization and its significance in gene expression are discussed.
已对一个82 kb的寄生曲霉基因组DNA区域进行了测序和注释，该区域代表了组织良好的黄曲霉毒素途径基因簇的完整序列。除了该基因簇中19个已报道和表征的黄曲霉毒素途径基因以及4个糖利用基因外，我们在此报告了6个新鉴定的基因，它们可能参与黄曲霉毒素的形成。讨论了这些基因的功能、基因簇组织及其在基因表达中的意义。
