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社区样本中焦虑和抑郁在孕期及产后的发展过程。

The course of anxiety and depression through pregnancy and the postpartum in a community sample.

作者信息

Heron Jonathan, O'Connor Thomas G, Evans Jonathan, Golding Jean, Glover Vivette

机构信息

University of Bristol, UK.

出版信息

J Affect Disord. 2004 May;80(1):65-73. doi: 10.1016/j.jad.2003.08.004.

Abstract

BACKGROUND

Postnatal and antenatal depression are a focus of considerable clinical and research attention, but little is known about the patterns of anxiety across this period.

METHODS

Self-reported anxiety and depression were assessed at 18 and 32 weeks gestation and 8 weeks and 8 months postnatally in a prospective longitudinal study of a community sample of women in England (n=8323).

RESULTS

The majority of cases of postnatal depression were preceded by antenatal depression; similarly, postnatal anxiety was preceded by antenatal anxiety. Despite the stability of anxiety and depression across this period, there was a mean decrease in both anxiety and depression. Finally, antenatal anxiety predicted postnatal depression at 8 weeks and 8 months, even after controlling for antenatal depression (OR=3.22, p<0.001).

LIMITATIONS

Data were based on self-report only and there was evidence of selective attrition.

CONCLUSION

The findings confirm that antenatal anxiety occurs frequently, overlaps with depression and increases the likelihood of postnatal depression.

摘要

背景

产后抑郁和产前抑郁是临床和研究关注的重点,但对于这一时期的焦虑模式知之甚少。

方法

在一项对英格兰社区女性样本(n = 8323)的前瞻性纵向研究中,在妊娠18周和32周以及产后8周和8个月时评估自我报告的焦虑和抑郁情况。

结果

大多数产后抑郁病例之前都有产前抑郁;同样,产后焦虑之前也有产前焦虑。尽管在此期间焦虑和抑郁情况较为稳定,但焦虑和抑郁均有平均下降。最后,即使在控制了产前抑郁之后,产前焦虑仍可预测产后8周和8个月时的产后抑郁(OR = 3.22,p < 0.001)。

局限性

数据仅基于自我报告,且有选择性损耗的证据。

结论

研究结果证实产前焦虑经常发生,与抑郁重叠,并增加了产后抑郁的可能性。

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