Heron Jonathan, O'Connor Thomas G, Evans Jonathan, Golding Jean, Glover Vivette
University of Bristol, UK.
J Affect Disord. 2004 May;80(1):65-73. doi: 10.1016/j.jad.2003.08.004.
Postnatal and antenatal depression are a focus of considerable clinical and research attention, but little is known about the patterns of anxiety across this period.
Self-reported anxiety and depression were assessed at 18 and 32 weeks gestation and 8 weeks and 8 months postnatally in a prospective longitudinal study of a community sample of women in England (n=8323).
The majority of cases of postnatal depression were preceded by antenatal depression; similarly, postnatal anxiety was preceded by antenatal anxiety. Despite the stability of anxiety and depression across this period, there was a mean decrease in both anxiety and depression. Finally, antenatal anxiety predicted postnatal depression at 8 weeks and 8 months, even after controlling for antenatal depression (OR=3.22, p<0.001).
Data were based on self-report only and there was evidence of selective attrition.
The findings confirm that antenatal anxiety occurs frequently, overlaps with depression and increases the likelihood of postnatal depression.
产后抑郁和产前抑郁是临床和研究关注的重点,但对于这一时期的焦虑模式知之甚少。
在一项对英格兰社区女性样本(n = 8323)的前瞻性纵向研究中,在妊娠18周和32周以及产后8周和8个月时评估自我报告的焦虑和抑郁情况。
大多数产后抑郁病例之前都有产前抑郁;同样,产后焦虑之前也有产前焦虑。尽管在此期间焦虑和抑郁情况较为稳定,但焦虑和抑郁均有平均下降。最后,即使在控制了产前抑郁之后,产前焦虑仍可预测产后8周和8个月时的产后抑郁(OR = 3.22,p < 0.001)。
数据仅基于自我报告,且有选择性损耗的证据。
研究结果证实产前焦虑经常发生,与抑郁重叠,并增加了产后抑郁的可能性。