Voetsch Andrew C, Van Gilder Thomas J, Angulo Frederick J, Farley Monica M, Shallow Sue, Marcus Ruthanne, Cieslak Paul R, Deneen Valerie C, Tauxe Robert V
Foodborne and Diarrheal Diseases Branch, Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Clin Infect Dis. 2004 Apr 15;38 Suppl 3:S127-34. doi: 10.1086/381578.
To determine the burden of Salmonella infections in the United States, Foodborne Diseases Active Surveillance Network (FoodNet) investigators conducted population-based active surveillance for culture-confirmed Salmonella infections during 1996-1999 at FoodNet laboratories. In addition, all clinical microbiology FoodNet laboratories were surveyed to determine their practices for isolating Salmonella. Telephone interviews were also conducted among residents of the FoodNet sites to determine the proportion of persons with diarrheal illness who sought medical care and the proportion who submitted stool specimens for bacterial culture. Using our model, we estimated that there were 1.4 million nontyphoidal Salmonella infections in the United States, resulting in 168,000 physician office visits per year during 1996-1999. Including both culture-confirmed infections and those not confirmed by culture, we estimated that Salmonella infections resulted in 15,000 hospitalizations and 400 deaths annually. These estimates indicate that salmonellosis presents a major ongoing burden to public health.
为确定美国沙门氏菌感染的负担情况，食源性疾病主动监测网络（FoodNet）的研究人员于1996 - 1999年期间在FoodNet实验室开展了基于人群的确诊沙门氏菌感染主动监测。此外，对所有FoodNet临床微生物实验室进行了调查，以确定其分离沙门氏菌的操作规范。还对FoodNet监测点的居民进行了电话访谈，以确定腹泻病患者寻求医疗救治的比例以及提交粪便标本进行细菌培养的比例。利用我们的模型，我们估计美国每年有140万例非伤寒型沙门氏菌感染，在1996 - 1999年期间每年导致16.8万人次就诊于医生办公室。将确诊感染和未确诊感染都计算在内，我们估计沙门氏菌感染每年导致1.5万人住院和400人死亡。这些估计表明，沙门氏菌病给公共卫生带来了持续的重大负担。
