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[白百破疫苗引起的铝过敏]

[Aluminum allergy caused by DTP vaccine].

作者信息

Nielsen A O, Kaaber K, Veien N K

机构信息

Hudklinikken, Herning.

出版信息

Ugeskr Laeger. 1992 Jun 29;154(27):1900-1.

PMID:1509548
Abstract

All children referred to two private dermatological practices from 1 Jan. 1985 to 31 Dec. 1990 who had pruritus and subcutaneous infiltrates in the areas of immunization with Di-Te-Pol vaccine were patch tested with a Finn Chamber or with 2% aqueous aluminium chloride. Di-Te-Pol vaccine contains aluminium hydroxide. Contact allergy to aluminium was demonstrated in 32 children (20 girls and 12 boys). Of the three patch test methods used, testing with 2% AlCl3 occluded with a Finn Chamber proved to be the most sensitive. Immunization of children who have been shown to be allergic to aluminium should be carried out with vaccines which do not contain aluminium.

摘要

1985年1月1日至1990年12月31日期间,所有转诊至两家私立皮肤科诊所、在接种白喉-破伤风-百日咳疫苗的免疫部位出现瘙痒和皮下浸润的儿童,均使用Finn Chamber或2%氯化铝水溶液进行斑贴试验。白喉-破伤风-百日咳疫苗含有氢氧化铝。32名儿童(20名女孩和12名男孩)被证实对铝有接触性过敏。在所使用的三种斑贴试验方法中,用Finn Chamber封闭的2% AlCl3试验被证明是最敏感的。已被证明对铝过敏的儿童应接种不含铝的疫苗。

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