Fukushima Atsushi, Shirakashi Motohiro, Yaoeda Kiyoshi, Funaki Shigeo, Funaki Haruko, Ofuchi Nobutaka, Abe Haruki
Department of Ophthalmology, Niigata University Faculty of Medicine, Niigata City, Niigata, Japan.
J Glaucoma. 2004 Apr;13(2):114-9. doi: 10.1097/00061198-200404000-00006.
To study whether the correlation between indices of Humphrey perimetry and Frequency Doubling Technology (FDT) perimetry differs in the early and later stages of glaucoma.
This study included 200 eyes of 200 patients with primary open-angle glaucoma or normal-tension glaucoma. The eyes were classified into the early and later stages by the median value (-4.51 dB) (Classification 1; n = 100 and 100, respectively) or the average value of the maximum and minimum values (-11.90 dB) (Classification 2; n = 165 and 35, respectively) of mean deviation (MD) obtained from a set of measurements with the Humphrey Full-Threshold 30-2 program in all eyes. The correlation between MD (H-MD) or pattern standard deviation (PSD) (H-PSD), as obtained from another set of measurements with the Humphrey Full-Threshold 30-2 program, and MD (F-MD) or PSD (F-PSD), as calculated by the Full-Threshold N-30 program of FDT perimetry, were evaluated using linear regression analysis.
Overall, H-MD and H-PSD significantly correlated with F-MD (r = 0.713; P < 0.001) and F-PSD (r = 0.731; P < 0.001), respectively. In each of Classifications 1 and 2, H-MD and H-PSD significantly correlated with F-MD and F-PSD, respectively, both in the early and later stages. However, in each classification, the correlation between H-MD and F-MD differed significantly between the two stages (Classification 1; P < 0.001; Classification 2, P = 0.003), while the correlation between H-PSD and F-PSD did not differ significantly between the two stages.
The degree of correlation between H-MD and F-MD differed between the early and later stages of glaucoma.
研究青光眼早期和晚期Humphrey视野计指标与倍频视野检查（FDT）指标之间的相关性是否存在差异。
本研究纳入了200例原发性开角型青光眼或正常眼压性青光眼患者的200只眼。根据所有眼使用Humphrey全阈值30-2程序进行的一组测量所得平均偏差（MD）的中位数（-4.51 dB）（分类1；分别为n = 100和100）或最大值与最小值的平均值（-11.90 dB）（分类2；分别为n = 165和35）将这些眼分为早期和晚期。使用线性回归分析评估从另一组使用Humphrey全阈值30-2程序测量所得的MD（H-MD）或模式标准差（PSD）（H-PSD）与通过FDT视野计全阈值N-30程序计算所得的MD（F-MD）或PSD（F-PSD）之间的相关性。
总体而言，H-MD和H-PSD分别与F-MD（r = 0.713；P < 0.001）和F-PSD（r = 0.731；P < 0.001）显著相关。在分类1和分类2中，H-MD和H-PSD在早期和晚期均分别与F-MD和F-PSD显著相关。然而，在每种分类中，H-MD与F-MD之间的相关性在两个阶段之间存在显著差异（分类1；P < 0.001；分类2，P = 0.003），而H-PSD与F-PSD之间的相关性在两个阶段之间无显著差异。
H-MD与F-MD之间的相关程度在早期和晚期有所不同。
