De Tarso Pierre-Filho Paulo, Gomes Paulo R P, Pierre Erika T L, Pierre Leandro M
Department of Ophthalmology, Santa Casa of Sobral, Sobral - Brazil.
Eur J Ophthalmol. 2010 May-Jun;20(3):538-41. doi: 10.1177/112067211002000328.
To evaluate the learning effect of frequency doubling technology (FDT) perimetry using the Humphrey Matrix perimeter in patients with open-angle glaucoma with no perimetric experience.
One eye each of 30 glaucoma patients who had no history of visual field testing underwent 3 Matrix tests using 24-2 program with full-threshold strategy. The parameters investigated to detect learning effect were test duration, reliability indexes, mean deviation (MD), pattern standard deviation (PSD), and the number of points with a p of <5% and <1% in the total and pattern deviation maps.
MD showed a larger defect at the first test (-13.64 +/- 1.63 dB) than at the second (-12.68 +/- 1.45 dB) and third (-11.69 +/- 1.48 dB) tests (p<0.05). A statistically significant reduction (p<0.05) in the number of points with a p <5% and <1% in the total deviation map was observed when repeating the examination. The values of test duration, PSD, fixation losses, false-positive rate, false-negative rate, and number of points with a p <5% and <1% in the pattern deviation map were not changed significantly (p>0.05).
Humphrey Matrix FDT perimetry showed a statistically significant learning effect on MD and the number of significantly depressed points of the total deviation map in glaucoma patients with no perimetric experience. It is probably necessary to obtain at least 3 repetitions to rule out the presence of a learning effect in such patients before providing useful results.
使用Humphrey Matrix视野计评估频率加倍技术（FDT）视野检查在无视野检查经验的开角型青光眼患者中的学习效果。
30例无视野检查史的青光眼患者的单眼，采用全阈值策略，使用24-2程序进行3次Matrix检查。用于检测学习效果的研究参数包括检查时长、可靠性指标、平均偏差（MD）、模式标准偏差（PSD），以及总偏差图和模式偏差图中p值<5%和<1%的点数。
MD在第一次检查时显示出比第二次（-12.68±1.45 dB）和第三次（-11.69±1.48 dB）检查时更大的缺损（-13.64±1.63 dB）（p<0.05）。重复检查时，观察到总偏差图中p<5%和<1%的点数有统计学意义的减少（p<0.05）。检查时长、PSD、固视丢失率、假阳性率、假阴性率，以及模式偏差图中p<5%和<1%的点数的值没有显著变化（p>0.05）。
Humphrey Matrix FDT视野检查在无视野检查经验的青光眼患者中，对MD和总偏差图中显著压低点数显示出统计学意义的学习效果。在提供有用结果之前，可能需要至少进行3次重复检查以排除此类患者存在学习效果的情况。
