Zein Wadih M, Bashshur Ziad F, Jaafar Rola F, Noureddin Baha' N
Children's National Medical Center, Washington, DC, USA.
Int Ophthalmol. 2010 Dec;30(6):683-9. doi: 10.1007/s10792-010-9400-1. Epub 2010 Oct 6.
To test the ability of frequency doubling technology (FDT) perimetry to reveal defects in the same field quadrants as detected by standard automated perimetry (SAP). Ninety-two eyes with open-angle glaucoma and documented visual field defects by threshold SAP (Octopus Dynamic strategy) also underwent threshold FDT testing after successfully passing the FDT screening test. All eyes revealed varying stages of SAP defects while only 80 revealed FDT damage: 31:21 eyes in the early field loss stage, 36:35 in the moderate field loss stage, and 25:24 in the severe field loss stage in SAP versus FDT, respectively. SAP was able to detect abnormalities in 74 and 79% of the superotemporal, and inferotemporal quadrants, respectively, while the corresponding FDT figures were 70 and 69% for the same quadrants (P < 0.05 each). With regards to the nasal hemifield, SAP detected defects in 73 and 81% of the superonasal and inferonasal quadrants, respectively, compared to 69 and 66% for FDT (P < 0.001 each). The test duration per individual eye was significantly shorter with FDT than with SAP (P < 0.05). As well as the already established lower sensitivity of FDT compared to SAP, this study also demonstrated the significantly poorer ability of FDT in detecting the same field quadrant defects, especially in the early stages of glaucomatous damage.
为测试倍频技术(FDT)视野检查法揭示与标准自动视野检查法(SAP)所检测到的相同视野象限缺损的能力。92只患有开角型青光眼且经阈值SAP(Octopus动态策略)记录有视野缺损的眼睛,在成功通过FDT筛查测试后,也接受了阈值FDT测试。所有眼睛均显示出不同阶段的SAP缺损,而只有80只显示出FDT损伤:在SAP与FDT中,早期视野缺损阶段分别为31:21只眼睛,中度视野缺损阶段为36:35只眼睛,重度视野缺损阶段为25:24只眼睛。SAP能够分别在74%和79%的颞上象限和颞下象限检测到异常,而相同象限的相应FDT数据分别为70%和69%(各P<0.05)。关于鼻侧半视野,SAP分别在73%和81%的鼻上象限和鼻下象限检测到缺损,而FDT分别为69%和66%(各P<0.001)。FDT检查每只眼睛的测试时间明显短于SAP(P<0.05)。除了已确定的FDT与SAP相比灵敏度较低外,本研究还表明FDT在检测相同视野象限缺损方面的能力明显较差,尤其是在青光眼损害的早期阶段。