[视网膜手术和眼部肿瘤治疗后的干眼症状]
[Dry eye symptoms following retinal surgery and ocular tumour therapy].
作者信息
Heimann H, Gochman R, Hellmich M, Bechrakis N E, Foerster M H
机构信息
Augenklinik, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin.
出版信息
Ophthalmologe. 2004 Nov;101(11):1098-104. doi: 10.1007/s00347-004-1033-1.
BACKGROUND
Dry eye symptoms can often be observed following vitreo-retinal operations, however, little is known about the frequency and severity of these postoperative problems.
METHODS
Examination of 140 patients following vitreo-retinal surgery ( n=31), brachytherapy ( n=76), proton beam radiation ( n=33) and controls ( n=54) using a questionnaire together with a clinical examination of the anterior segment, tear break-up time and a Schirmer test.
RESULTS
Of the treated patients 63% complained of dry eye symptoms versus 40% of the controls ( p=0.004). The tear break-up time was decreased in treated patients ( p<0.001, medians: 15 vs. 20 s). No significant difference was seen on the Schirmer test ( p=0.825; medians: 12 vs. 12 mm).
CONCLUSIONS
Dry eye symptoms are a common postoperative complication following vitreo-retinal surgery and ocular tumour therapy.
背景
玻璃体视网膜手术后常可观察到干眼症状，然而，对于这些术后问题的发生率和严重程度知之甚少。
方法
采用问卷以及眼前节临床检查、泪膜破裂时间和泪液分泌试验，对140例接受玻璃体视网膜手术（n = 31）、近距离放射治疗（n = 76）、质子束放疗（n = 33）的患者及对照组（n = 54）进行检查。
结果
治疗组患者中有63%主诉有干眼症状，而对照组为40%（p = 0.004）。治疗组患者的泪膜破裂时间缩短（p < 0.001，中位数：15秒对20秒）。泪液分泌试验未见显著差异（p = 0.825；中位数：12毫米对12毫米）。
结论
干眼症状是玻璃体视网膜手术和眼部肿瘤治疗后常见的术后并发症。
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