Hara Shuya, Kojima Takashi, Ishida Reiko, Goto Eiki, Matsumoto Yukihiro, Kaido Minako, Shimazaki Jun, Dogru Murat, Tsubota Kazuo
Department of Ophthalmology, Social Insurance Chukyo Hospital, Aichi, Japan.
Optom Vis Sci. 2011 Sep;88(9):1112-8. doi: 10.1097/OPX.0b013e3182223573.
To evaluate the efficacy of surgical treatment for conjunctivochalasis using the Tear Film Stability Analysis System.
Fifteen eyes of 15 patients (74.5 ± 4.8 years; 14 females and 1 male) who had surgical reconstruction of the tear meniscus for conjunctivochalasis underwent evaluation with a symptom questionnaire, Schirmer I test, fluorescein tear film break-up time (FBUT), and break-up time index (BUI) measurement by Tear Film Stability Analysis System examinations that were performed preoperatively and 3 months after the surgery. Changes of these tear parameters were statistically analyzed using the paired t test.
After the surgery, the mean FBUT and BUI values significantly improved from 5.7 ± 3.2 s and 42.8 ± 18.7, respectively, to 8.4 ± 2.5 s and 60.7 ± 16.5, respectively (FBUT, p = 0.0438; BUI, p = 0.0036). The mean Schirmer test value showed no significant changes before and after surgery (p = 0.9064). Fourteen eyes (93.3%) had improvement of ocular symptoms after surgery. One eye (6.7%) with no improvement of ocular symptoms, FBUT, and BUI after surgery appeared to have aqueous tear deficiency.
Surgical treatment for conjunctivochalasis was associated with improvement of tear stability and clinical dry eye symptoms.
使用泪膜稳定性分析系统评估结膜松弛症手术治疗的疗效。
对15例（74.5±4.8岁；14例女性，1例男性）因结膜松弛症行泪液半月皱襞手术重建的患者的15只眼进行了术前及术后3个月的评估，包括症状问卷、Schirmer I试验、荧光素泪膜破裂时间（FBUT）以及通过泪膜稳定性分析系统测量破裂时间指数（BUI）。使用配对t检验对这些泪液参数的变化进行统计学分析。
术后，平均FBUT值和BUI值分别从5.7±3.2秒和42.8±18.7显著提高到8.4±2.5秒和60.7±16.5（FBUT，p = 0.0438；BUI，p = 0.0036）。Schirmer试验平均值在手术前后无显著变化（p = 0.9064）。14只眼（93.3%）术后眼部症状改善。1只眼（6.7%）术后眼部症状、FBUT和BUI均无改善，似乎存在水样泪液缺乏。
结膜松弛症的手术治疗与泪液稳定性及临床干眼症状的改善相关。
