Bukhari Amal, Ajlan Radwan, Alsaggaf Husain
Department of Ophthalmology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Orbit. 2009;28(6):392-7. doi: 10.3109/01676830903074095.
To estimate the prevalence of dry eye disease in the normal non-complaining population.
Prospective systematic random sampling study of 251 subjects who accompanied patients with appointments to the eye clinic. Interviewers administered a dry eye symptoms and risk factor questionnaire. Tear film break up time, fluorescein corneal staining and Schirmer's test were performed. Slit lamp examination to evaluate the lid margins, Meibomian glands and ocular surface structures was also performed.
Dry eye was diagnosed in 234 (93.2%) subjects on the basis of presence of one or more symptoms occurring often or most of the time, together with one or more of the following signs: tear film break up time < or = 10 seconds, fluorescein corneal staining > or = grade 1 and Schirmer test score < or = 5 mm. There was no statistically significant association between dry eye with advancing age or gender. Blepharitis was detected in 215 (91.9%) of the dry eye cases. Smoking was found to be the second most common risk factor as 18.8% of the dry eye cases were smokers. Sicca syndrome was found in 24.4% of the subjects.
Dry eye is very prevalent disease. Blepharitis was found to be very common among dry eye cases. There was no statistically significant association between dry eye and age or gender in our study population.
评估正常无眼部不适人群中干眼疾病的患病率。
对251名陪同患者到眼科门诊就诊的受试者进行前瞻性系统随机抽样研究。访员发放干眼症状及危险因素问卷。进行泪膜破裂时间、荧光素角膜染色和泪液分泌试验。还进行裂隙灯检查以评估睑缘、睑板腺和眼表结构。
234名（93.2%）受试者被诊断为干眼，依据是经常或大部分时间出现一种或多种症状，以及以下一种或多种体征：泪膜破裂时间≤10秒、荧光素角膜染色≥1级和泪液分泌试验评分≤5毫米。干眼与年龄增长或性别之间无统计学显著关联。215例（91.9%）干眼病例检测出睑缘炎。吸烟是第二常见的危险因素，18.8%的干眼病例为吸烟者。24.4%的受试者发现有干燥综合征。
干眼是一种非常普遍的疾病。睑缘炎在干眼病例中非常常见。在我们的研究人群中，干眼与年龄或性别之间无统计学显著关联。
