Pistelli Riccardo, Baldari Fiammetta, Sammarro Sandra
Servizio di Fisiopatologia Respiratoria, Istituto di Medicina Interna e Geriatria, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, Roma.
Ann Ist Super Sanita. 2003;39(4):485-93.
Many personal and environmental risk factors are associated to increased prevalence and severity of chronic obstructive pulmonary disease (COPD). In this review, we shortly describe most of these risk factors, aiming at defining each factor as causative or modifier of the natural history of the disease. It is clear that the environmental risk factors do have an outstanding relevance for both the initiation and the evolution of COPD. This review focuses on the crucial importance of prevention in order to decrease the public health burden of COPD in the western countries during the next decades.
许多个人和环境风险因素与慢性阻塞性肺疾病（COPD）患病率和严重程度的增加相关。在本综述中，我们简要描述了其中的大多数风险因素，旨在确定每个因素是该疾病自然史的病因还是影响因素。显然，环境风险因素对于COPD的发病和发展都具有突出的相关性。本综述着重强调预防的关键重要性，以便在未来几十年减轻西方国家COPD的公共卫生负担。
