Nakamura Yoichi, Obase Yasushi, Suyama Naofumi, Miyazaki Yoshitsugu, Ohno Hideaki, Oka Mikio, Takahashi Mitsuyoshi, Kohno Shigeru
Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki.
Intern Med. 2004 Mar;43(3):263-7. doi: 10.2169/internalmedicine.43.263.
Four habitual drinking and smoking patients with pulmonary tuberculosis who were thought to have had no contact with one another were admitted to our hospital. During admission, we found that they were regular visitors of the same bar. To investigate the possibility of outbreak, we analyzed the tuberculosis isolates from them by restriction fragment length polymorphism. Such analysis showed identical chromosomal DNA restriction patterns of these 4 culture isolates. We concluded that these patients were considered to represent a mini-outbreak of pulmonary tuberculosis, although there was little, if any, contact among them while in or out of the bar.
4名患有肺结核且被认为彼此无接触的酗酒和吸烟患者入住我院。入院期间，我们发现他们是同一家酒吧的常客。为调查爆发的可能性，我们通过限制性片段长度多态性分析了他们的结核分枝杆菌分离株。此类分析显示这4株培养分离株具有相同的染色体DNA限制性图谱。我们得出结论，尽管这些患者在酒吧内外几乎没有接触，但他们被认为代表了一次肺结核的小规模爆发。
