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临床诊断为“良性”的乳腺肿块:隐匿的肉瘤?——病例报告及文献综述

Clinically 'benign' breast lumps: sarcoma in hiding?--Case reports and literature review.

作者信息

Teo T, Wee S B

机构信息

Singapore Health Services, Mt Elizabeth Medical Centre.

出版信息

Ann Acad Med Singap. 2004 Mar;33(2):270-4.

Abstract

Breast sarcoma is a very rare entity that accounts for less than 1% of all breast malignancies and less than 5% of all soft tissue tumours. Although uncommon, we highlight 2 recent cases encountered at our centre. The aim is to emphasise their apparent benign appearance on physical examination, so that readers will be alerted in a similar clinical setting. Medline was used to search for relevant articles concerning the pathology, treatment modalities and long-term prognosis of patients with this rare illness. We also reviewed soft tissue sarcomas found elsewhere. Articles relating to phyllodes tumour were excluded or only relevant sections used. We discuss the controversy regarding axillary lymph node clearance and the use of radiotherapy. Despite conflicting reports and lack of clinical studies, we believe that a simple mastectomy will suffice as adequate treatment, hence avoiding the undesirable side effects of chemotherapy or radiotherapy.

摘要

乳腺肉瘤是一种非常罕见的疾病,占所有乳腺恶性肿瘤的比例不到1%,占所有软组织肿瘤的比例不到5%。尽管并不常见,但我们重点介绍了我们中心最近遇到的2例病例。目的是强调它们在体格检查中看似良性的外观,以便读者在类似的临床情况下能够得到警示。我们使用医学在线数据库(Medline)搜索有关这种罕见疾病患者的病理学、治疗方式和长期预后的相关文章。我们还回顾了在其他地方发现的软组织肉瘤。与叶状肿瘤相关的文章被排除,或仅使用相关部分。我们讨论了关于腋窝淋巴结清扫和放疗使用的争议。尽管有相互矛盾的报道且缺乏临床研究,但我们认为单纯乳房切除术就足以作为充分的治疗方法,从而避免化疗或放疗带来的不良副作用。

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