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[罕见乳腺肿瘤]

[Rare breast tumors].

作者信息

Haberthür F, Torhorst J, Feichter G E

机构信息

Universitäts-Frauenklinik, Basel.

出版信息

Ther Umsch. 1993 May;50(5):359-65.

PMID:8397448
Abstract

The cystosarcoma phylloides, like the sarcoma, represents 0.3 to 0.9% of all tumors of the breast. The clinical features include two different developments, one phase with increase and the other without. After removal of tumors, there are frequent recurrences. The unique therapy is for that reason to remove the lump with a margin in healthy tissue. The sarcoma of the breast represents only 0.2 to 1% of all mammary malignancies. This study reports four cases, including two osteosarcomas, one fibro- and one malignant fibrous sarcoma. The treatment of choice was mastectomy in three cases with dissection of axillary lymph nodes. The remaining patient was treated by simple mastectomy only. One patient demonstrated local recurrence and died. The remaining three patients developed neither metastases nor local recurrence. They are still alive with periods of observation between 18 months and 17 years. As first-line treatment wide local excision or simple mastectomy is recommended. Dissection of the axillary lymphatics, adjuvant radiotherapy or chemotherapy have no proven value in the treatment of breast sarcoma.

摘要

叶状囊肉瘤与肉瘤一样,占所有乳腺肿瘤的0.3%至0.9%。其临床特征包括两种不同的发展情况,一种是增大期,另一种是无增大期。肿瘤切除后,复发频繁。因此,唯一的治疗方法是在健康组织中带边缘切除肿块。乳腺肉瘤仅占所有乳腺恶性肿瘤的0.2%至1%。本研究报告了4例病例,包括2例骨肉瘤、1例纤维肉瘤和1例恶性纤维肉瘤。3例患者的首选治疗方法是乳房切除术并清扫腋窝淋巴结。其余1例患者仅接受了单纯乳房切除术。1例患者出现局部复发并死亡。其余3例患者既未发生转移也未出现局部复发。他们仍存活,观察期在18个月至17年之间。作为一线治疗,建议进行广泛局部切除或单纯乳房切除术。腋窝淋巴结清扫、辅助放疗或化疗在乳腺肉瘤治疗中尚未证实有价值。

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