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初级保健中的高血压管理与控制:对14个州20家医疗机构的研究

Hypertension management and control in primary care: a study of 20 practices in 14 states.

作者信息

Ornstein Steven M, Nietert Paul J, Dickerson Lori M

机构信息

Department of Family Medicine, Medical University of South Carolina, Charleston 29425, USA.

出版信息

Pharmacotherapy. 2004 Apr;24(4):500-7. doi: 10.1592/phco.24.5.500.33359.

Abstract

STUDY OBJECTIVE

To describe the management and control of hypertension in primary care practice.

DESIGN

Retrospective medical record review.

SETTING

Twenty primary care practices in 14 states.

PATIENTS

Thirteen thousand forty-seven patients with hypertension.

MEASUREMENTS AND MAIN RESULTS

Diagnoses, drugs prescribed, and blood pressure readings were extracted from the electronic medical record at each practice in the study. For patients with hypertension and comorbid diagnoses, the most recent blood pressure and antihypertensive drugs prescribed were determined. Analyses assessed the blood pressure control rates and the association between control and demographic variables, frequency of visits to the practice site, and pharmacologic treatment patterns. Among the 20 practices in the study, 13,047 patients had received a diagnosis of hypertension and their blood pressures had been measured within the previous 12 months. One third of the patients had comorbid coronary heart disease, diabetes mellitus, heart failure, and/or renal insufficiency. The most recent blood pressure reading was below 140/90 in half the patients. Control was associated with age 60 years or younger, female sex, more than one visit to the practice, more than one comorbidity, and type of practice (p<0.01, logistic regression). Wide variability was noted among practices in the use of multiagent antihypertensive therapy, and in antihypertensive therapy by drug class. Among patients without comorbidity treated with one drug, systolic blood pressure did not differ significantly by drug class. Diastolic blood pressure was slightly lower in patients prescribed thiazide diuretics than in those prescribed angiotensin receptor blockers (p=0.03, analysis of covariance).

CONCLUSION

Blood pressure control in primary care practice can be much better than reports usually indicate. Good control in this study was not due to specific drug choice, but instead may have been due to regular monitoring of blood pressure and motivation of the practice to improve patient care.

摘要

研究目的

描述基层医疗实践中高血压的管理与控制情况。

设计

回顾性病历审查。

地点

14个州的20家基层医疗诊所。

患者

13047例高血压患者。

测量指标及主要结果

从研究中的每家诊所的电子病历中提取诊断结果、所开药物及血压读数。对于患有高血压及合并其他诊断的患者,确定其最近的血压及所开的降压药。分析评估了血压控制率以及控制与人口统计学变量、到诊所就诊的频率和药物治疗模式之间的关联。在该研究的20家诊所中,有13047例患者被诊断为高血压,且在过去12个月内测量过血压。三分之一患者合并有冠心病、糖尿病、心力衰竭和/或肾功能不全。一半患者最近的血压读数低于140/90。血压得到控制与年龄60岁及以下、女性、到诊所就诊次数超过一次、合并症超过一种以及诊所类型有关(p<0.01,逻辑回归)。在多药联合降压治疗的使用以及按药物类别进行的降压治疗方面,各诊所之间存在很大差异。在仅使用一种药物治疗且无合并症的患者中,不同药物类别之间收缩压无显著差异。使用噻嗪类利尿剂的患者舒张压略低于使用血管紧张素受体阻滞剂的患者(p=0.03,协方差分析)。

结论

基层医疗实践中的血压控制情况可能比通常报告的要好得多。本研究中的良好控制并非归因于特定的药物选择,而是可能归因于对血压的定期监测以及诊所改善患者护理的积极性。

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