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埃塞俄比亚西南部吉马大学医学中心糖尿病合并高血压患者的血压控制及其影响因素

Blood pressure control and its determinants among diabetes mellitus co-morbid hypertensive patients at Jimma University medical center, South West Ethiopia.

作者信息

Muleta Sintayehu, Melaku Tsegaye, Chelkeba Legese, Assefa Desta

机构信息

Department of Clinical Pharmacy, School of Pharmacy, Institute of Health, Jimma University, P.O.Box:378, Jimma, Oromia Ethiopia.

Department of Pharmaceutics, School of Pharmacy, Institute of Health, Jimma University, P.O.Box:378, Jimma, Oromia Ethiopia.

出版信息

Clin Hypertens. 2017 Dec 27;23:29. doi: 10.1186/s40885-017-0085-x. eCollection 2017.

Abstract

BACKGROUND

Hypertension is the major contributor to cardiovascular diseases related morbidity and mortality. Blood pressure is not well controlled in the majority of patients with both diabetes and hypertension. The main objective of this study was to assess blood pressure control and its determinants among diabetes mellitus co- morbid hypertensive ambulatory patients.

METHODS

Hospital based cross sectional study was conducted among diabetes mellitus co-morbid hypertensive ambulatory adult patients based on the inclusion criteria. Patient specific data was collected using structured data collection tool. Data was analyzed using statistical software package, SPSS version 20.0. To identify the independent predictors of blood pressure control, multiple stepwise backward logistic regression analysis was done. Statistical significance was considered at -value <0.05. Patient's written informed consent was obtained after explaining the purpose of the study. Patients were informed about confidentiality of the information obtained.

RESULTS

From a total of 131 study participants 51.14% were males with the mean (SD) age of the 50.69 ± 13.71. The mean duration of time since the diagnosis of hypertension was 7.44 ± 5.11 years. The mean (SD) SBP was 149.79 ± 16.32 mmHg, while the mean (SD) DBP was 89.77 ± 9.34 mmHg. More than one fourth (25.20%) of study participants had a controlled SBP, while about 27.48% had a controlled DBP. The overall control of BP was achieved in about 57 (43.51%) of the study participants. Older age (≥50 years) (AOR = 2.06; 95% CI: 2.65-7.79;  = 0.002), female gender (AOR = 1.42; 95% CI: 1.19-2.14;  = 0.042), duration of hypertension (AOR = 2.88, 95% CI: 1.27, 8.31,  = 0.02), non-adherence (AOR 2.05; 95% CI: 2.61-9.33;  = 0.01) and uncontrolled blood sugar(AOR = 1.65; 95% CI: 2.14-3.32;  = 0.04) are independent predictors for uncontrolled blood pressure.

CONCLUSIONS

Blood pressure control to target goal was suboptimal in the study area. Diabetic patients who were older, female, live longer duration with hypertension, non-adherent to their medications and poor glycemic control were more likely to have uncontrolled BP. Therefore, more effort should be dedicated to control the blood pressure in diabetics.

摘要

背景

高血压是心血管疾病相关发病和死亡的主要促成因素。大多数糖尿病合并高血压患者的血压控制不佳。本研究的主要目的是评估糖尿病合并高血压门诊患者的血压控制情况及其决定因素。

方法

基于纳入标准,对糖尿病合并高血压门诊成年患者进行了一项基于医院的横断面研究。使用结构化数据收集工具收集患者特定数据。数据使用统计软件包SPSS 20.0进行分析。为了确定血压控制的独立预测因素,进行了多步逐步向后逻辑回归分析。当P值<0.05时认为具有统计学意义。在解释研究目的后获得了患者的书面知情同意。告知患者所获信息的保密性。

结果

在总共131名研究参与者中,51.14%为男性,平均(标准差)年龄为50.69±13.71岁。自诊断高血压以来的平均时间为7.44±5.11年。平均(标准差)收缩压为149.79±16.32mmHg,而平均(标准差)舒张压为89.77±9.34mmHg。超过四分之一(25.20%)的研究参与者收缩压得到控制,而约27.48%的参与者舒张压得到控制。约57名(43.51%)研究参与者实现了血压的总体控制。年龄较大(≥50岁)(调整后比值比[AOR]=2.06;95%置信区间[CI]:2.65 - 7.79;P=0.002)、女性(AOR=1.42;95%CI:1.19 - 2.14;P=0.042)、高血压病程(AOR=2.88,95%CI:1.27,8.31,P=0.02)、不依从(AOR 2.05;95%CI:2.61 - 9.33;P=0.01)和血糖未控制(AOR=1.65;95%CI:2.14 - 3.32;P=0.04)是血压未控制的独立预测因素。

结论

研究区域内血压控制至目标水平的情况次优。年龄较大、女性、高血压病程较长、不坚持服药以及血糖控制不佳的糖尿病患者更有可能血压未得到控制。因此,应更加努力控制糖尿病患者的血压。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01f7/5744392/57a3cb8b50c0/40885_2017_85_Fig1_HTML.jpg

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