Hodapp Robert M
Peabody College & John F. Kennedy Center for Research on Human Development, Peabody Box 328, Vanderbilt University, Nashville, Tennessee 37203, USA.
J Autism Dev Disord. 2004 Feb;34(1):29-34. doi: 10.1023/b:jadd.0000018071.02942.00.
Different genetic disorders predispose individuals to display specific, etiology-related profiles, personalities, and maladaptive behaviors. Using groups with genetic etiologies as stand-ins or proxies for a specific behavior or set of behaviors, one can then examine how others in the child's environment react and whether such reactions are limited to a particular disorder or occur generally to all individuals showing that behavior. Just as twins, adopted, and institutionalized children have all been used as natural experiments to tell us about typical development, so too can groups with specific genetic syndromes help us to understand the nature and mechanisms of the reactions and behaviors of others.
不同的遗传疾病使个体易于表现出特定的、与病因相关的特征、性格和适应不良行为。以具有遗传病因的群体作为特定一种或一组行为的替身或代表,进而可以研究儿童所处环境中的其他人如何做出反应,以及这种反应是否仅限于某一特定疾病,还是普遍发生在所有表现出该行为的个体身上。正如双胞胎、领养儿童和福利院儿童都被用作自然实验来向我们揭示典型发育情况一样,患有特定遗传综合征的群体也能够帮助我们理解他人反应和行为的本质及机制。