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良性转移性平滑肌瘤与淋巴管平滑肌瘤病:性别特异性疾病?

Benign metastasizing leiomyoma and lymphangioleiomyomatosis: sex-specific diseases?

作者信息

Pitts Shannon, Oberstein Elana M, Glassberg Marilyn K

机构信息

Department of Internal Medicine, University of Rochester School of Medicine, Strong Memorial Hospital, 6704 Setters Run, Rochester, NY 14564, USA.

出版信息

Clin Chest Med. 2004 Jun;25(2):343-60. doi: 10.1016/j.ccm.2004.01.014.

DOI:10.1016/j.ccm.2004.01.014
PMID:15099894
Abstract

The striking similarity between benign metastasizing leiomyoma and lymphangioleiomyomatosis is that they both affect young women. This observation underscores the importance of gender-dependent variables in disease and our lack of understanding of gender differences. Many researchers are currently investigating the link between disease and hormone levels in the body. The beneficial role of estrogens remains in question in pulmonary medicine, and further ongoing research should help to define the role of hormones in the lung.

摘要

良性转移性平滑肌瘤和淋巴管平滑肌瘤病之间显著的相似之处在于,它们都影响年轻女性。这一观察结果凸显了疾病中性别相关变量的重要性以及我们对性别差异缺乏了解。目前许多研究人员正在研究疾病与体内激素水平之间的联系。雌激素在肺病中的有益作用仍存在疑问,正在进行的进一步研究应有助于明确激素在肺部的作用。

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