Dumarey C, Sket D, Joseph D, Boquet P
C R Acad Hebd Seances Acad Sci D. 1975 Apr 7;280(13):1633-5.
It is confirmed that N. nigricollis venom contains several phospholipases one of these is a basic phospholipase A. This enzyme is toxic for mice when injected intravenously. In vitro it reacts on egg yolk lecithin producing lysolecithin and prevents the phenomenon of blood clotting. An immunological identity has been established between this basic phospholipase and two acidic phospholipases present in the same venom.
已证实黑颈眼镜蛇毒液含有几种磷脂酶,其中一种是碱性磷脂酶A。静脉注射时,这种酶对小鼠有毒。在体外,它作用于蛋黄卵磷脂产生溶血卵磷脂,并阻止血液凝固现象。已确定这种碱性磷脂酶与同一毒液中存在的两种酸性磷脂酶具有免疫同一性。