黑颈眼镜蛇和中华眼镜蛇蛇毒磷脂酶A2的精氨酸修饰对酶活性、致死性及抗凝作用的影响 - Suppr | 超能文献

Effects of arginine modification of Naja nigricollis and Naja naja atra snake venom phospholipases A2 on enzymatic activity, lethality and anticoagulant action.

作者信息

Condrea E, Rapuano B E, Fletcher J E, Yang C C, Rosenberg P

出版信息

Toxicon. 1981;19(5):721-5. doi: 10.1016/0041-0101(81)90109-4.

DOI:10.1016/0041-0101(81)90109-4

Abstract

摘要

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Effects of arginine modification of Naja nigricollis and Naja naja atra snake venom phospholipases A2 on enzymatic activity, lethality and anticoagulant action.黑颈眼镜蛇和中华眼镜蛇蛇毒磷脂酶A2的精氨酸修饰对酶活性、致死性及抗凝作用的影响

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Effects of modification of tyrosines 3 and 62 (63) on enzymatic and toxicological properties of phospholipases A2 from Naja nigricollis and Naja naja atra snake venoms.酪氨酸3和62（63）的修饰对黑颈眼镜蛇和中华眼镜蛇蛇毒磷脂酶A2的酶学和毒理学特性的影响。

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Factors influencing the hemolysis of human erythrocytes by cardiotoxins from Naja naja kaouthia and Naja naja atra venoms and a phospholipase A2 with cardiotoxin-like activities from Bungarus fasciatus venom.影响眼镜王蛇毒和眼镜蛇毒中的心毒素以及银环蛇毒中具有心毒素样活性的磷脂酶A2对人红细胞溶血作用的因素。

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Effect of modification of one histidine residue on the enzymatic and pharmacological properties of a toxic phospholipase A2 from Naja nigricollis snake venom and less toxic phospholipases A2 from Hemachatus haemachatus and Naja atra snake venoms.一个组氨酸残基的修饰对来自黑颈眼镜蛇蛇毒的有毒磷脂酶A2以及来自鼓腹咝蝰和中华眼镜蛇蛇毒的低毒磷脂酶A2的酶学和药理学特性的影响。

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Effect of carboxylate group modification on enzymatic and cardiotoxic properties of snake venom phospholipases A2.羧基修饰对蛇毒磷脂酶A2酶活性和心脏毒性的影响

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The relationship between high-affinity noncatalytic binding of snake venom phospholipases A2 to brain synaptic plasma membranes and their central lethal potencies.蛇毒磷脂酶A2与脑突触质膜的高亲和力非催化结合与其中枢致死效力之间的关系。

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In vivo synergy of cardiotoxin and phospholipase A2 from the elapid snake Naja mossambica mossambica.来自莫桑比克喷毒眼镜蛇的心脏毒素与磷脂酶A2在体内的协同作用。

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Comparison of a relatively toxic phospholipase A2 from Naja nigricollis snake venom with that of a relatively non-toxic phospholipase A2 from Hemachatus haemachatus snake venom--II. Pharmacological properties in relationship to enzymatic activity.黑颈眼镜蛇蛇毒中一种相对有毒的磷脂酶A2与拟眼镜蛇蛇毒中一种相对无毒的磷脂酶A2的比较——II. 与酶活性相关的药理学特性

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